摘要
目的探讨右美托咪定滴鼻在小儿术前麻醉镇静中的应用效果。方法将行外科手术治疗的50例小儿患者随机分为观察组和对照组,每组各25例,观察组采用右美托咪定滴鼻给药诱导麻醉,对照组采用咪达唑仑实施麻醉诱导,观察比较两组患者生命体征及镇静效果。结果术中10 min时,对照组患者呼吸频率(RR)低于观察组,心率(HR)高于观察组(P<0.05);治疗过程中,观察组患者HR和对照组患者RR明显降低(P<0.05);观察组患儿不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论与咪达唑仑相比,右美托咪定滴鼻对患儿生命体征几乎不产生严重影响,且不良反应发生率低,能较好地促进手术平稳进行。
Objective To investigate the effect of dexmedetomidine in the preoperative anesthesia and sedation in children. Methods 50 cases of pediatric patients undergoing surgical treatment were randomly divided into observation group and control group. In the observation group,anesthesia was induced by intramuscular injection of dexmedetomidine. In the control group,midazolam was induced by anesthesia, The vital signs and sedation of two groups were observed and compared. Results During 10 min,the control group of patients with RR than in the observation group, the level of HR was higher than the observation group（P〈0.05）. The course of treatment,patients in the observation group and the control group of HR patients with RR were significantly lower（P〈0.05）. The incidence of adverse reactions in the observation group was lower than that in the control group（P〈0.05）. Conclusion Compared with midazolam,dexmedetomidine has little effect on the vital signs of children, and the incidence of adverse reactions is low, which can promote the operation smoothly.
出处
《中国卫生标准管理》
2016年第24期177-179,共3页
China Health Standard Management
关键词
右美托咪定
咪达唑仑
小儿麻醉
Dexmedetomidine
Midazolam
Pediatric anesthesia
