摘要
目的观察甘海胃康胶囊联合替普瑞酮治疗慢性浅表性胃炎的临床疗效。方法选取内蒙古自治区中医医院2015年2月—2016年8月接诊的慢性浅表性胃炎患者86例,随机分为对照组和治疗组,每组各43例。对照组饭后口服替普瑞酮胶囊,50 mg/次,3次/d;治疗组在对照组的基础上口服甘海胃康胶囊,6粒/次,3次/d。两组患者均连续治疗3周。比较两组临床疗效、胃黏膜修复和中医证候评分情况。结果治疗后,对照组和治疗组总有效率分别为86.05%和93.02%,两组比较差异具有统计学意义(P<0.05)。治疗后,两组患者胃黏膜修复和中医证候评分均较治疗前明显降低,同组比较差异具有统计学意义(P<0.05)。且与对照组相比,治疗组上述评分降低的更显著,两组比较差异具有统计学意义(P<0.05)。结论甘海胃康胶囊联合替普瑞酮治疗慢性浅表性胃炎临床疗效确切,症状改善明显,具有一定的临床推广应用价值。
Objective To observe the clinical curative effect of Ganhai Weikang Capsules combined with teprenone in treatment of chronic superficial gastritis. Methods Patients （86 cases） with chronic superficial gastritis in Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine from February 2015 to August 2016 were randomly divided into the control and treatment groups, and each group had 43 cases. The patients in the control group were po administered with Teprenone Capsules, 50 mg/time, three times daily. The patients in the treatment group werepo administered with Ganhai Weikang Capsules on the basis of the control group, 6 grains/time, three times daily. After treatment, the clinical efficacy, gastric mucosal repair and TCM syndrome scores in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment group were 86.05% and 93.02%, respectively, and there were differences between two groups （P 〈 0.05）. After treatment, gastric mucosal repair and TCM syndrome scores in two groups were significantly decreased, and the difference was statistically significant in the same group （P 〈 0.05）. And compared with the control group, these scores in the treatment group were significantly lower than those in the control group, with significant difference between two groups （P 〈 0.05）. Conclusion Ganhai Weikang Capsules combined with teprenone has an obvious curative effect in treatment of chronic superficial gastritis with significantly improved symptoms, which has a certain clinical application value.
出处
《现代药物与临床》
CAS
2016年第12期1921-1924,共4页
Drugs & Clinic
关键词
甘海胃康胶囊
替普瑞酮胶囊
慢性浅表性胃炎
临床疗效
胃黏膜
中医证候
Ganhai Weikang Capsules
Teprenone Capsules
chronic superficial gastritis
clinical curative effect
gastric mucosal
TCM syndrome
