摘要
目的探讨噻托溴铵、普米克令舒及万托林在老年慢性阻塞性肺病加重期临床治疗效果及安全性。方法选取2014-12~2015-12该院诊治的80例老年慢性阻塞性肺部加重期患者,根据随机数字表法将患者分为对照组和治疗组两组,每组40例。对照组采用普米克令舒及万托林治疗,治疗组在对照组基础上联合噻托溴铵治疗,治疗10 d,比较两组临床疗效。结果治疗组治疗后喘憋、退热、咳嗽、干湿啰音消失时间以及住院时间显著短于对照组(P<0.05);治疗组药物不良反应发生率为7.5%,显著低于对照组的17.5%(P<0.05)。结论老年慢性阻塞性肺部加重期患者用普米克令舒及万托林治疗基础上联合噻托溴铵治疗效果较好,值得推广应用。
Objective To investigate the clinical effect and safety of tiotropium, Pulmicort and Ventolin onelderly patients with acute exacerbation of chronic obstructive pulmonary disease （COPD）. Methods Eighty elderly patients with acute exacerbation from December 2014 to December 2015 were randomly divided into two groups ac- cording to the different treatment methods, with 40 cases in each group. The control group was treated with Pulmicort and Ventolin. The experimental group was treated with tiotropium on basis of the therapy in the control group. Results The disappearance time of wheezing, fever, cough, dry and wet lung rales and the length of hospital stay in the exper- imental group were significantly shorter than those in the control group after the treatment（P 〈 0.05 ） ; The incidence of adverse reactions （ 7.5 % ） was significantly lower than that in the control group （ 17.5 % ） （ P 〈 0.05 ）. Conclusion The combination treatment of Pulmicort , Ventolin and tiotropium is safe and effective in the treatment of acute exacer- bation of COPD.
出处
《中国临床新医学》
2017年第1期64-66,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
关键词
噻托溴铵
普米克令舒
万托林
老年慢性阻塞性肺病
疗效
安全性
Tiotropium
Pulmicort
Ventolin
Elderly patients with chronic obstructive pulmonary dis- ease
Treatment
Safety
