摘要
目的研究狭叶金粟兰Chloranthus angustifolius地上部分的化学成分。方法使用多种柱色谱技术进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果从狭叶金粟兰地上部分甲醇提取物的醋酸乙酯萃取部位分离得到8个化合物,分别鉴定为1-乙酰氧基2,3,4,5-四羟基-5-对甲氧基苯基戊烷(1)、(E)-5-(4-甲氧基苯基)-4-烯-1,2,3-三羟基戊醇(2)、异嗪皮啶(3)、(-)-二氢脱氢二松柏醇(4)、(±)-赤式-愈创木酚基甘油-4'-二氢松柏醇醚(5)、(-)-rosiridol(6)、(4S)-对薄荷烯4,7-二醇(7)、地芰普内酯(8)。结论化合物1和2为新化合物,分别命名为金粟兰戊醇和金粟兰烯醇,化合物3~8均为首次从该植物中分离得到。
Objective To studythechemical constituents from theaerial parts of Chlo ranthusangustifolius.Methods The chemical constituents were isolated by various chromatography techniques and their structures were elucidated on the basis of physiochemical properties and spectrascopic analysis. Results Eight compounds were isolated and identified as 1-acetoxy-2,3,4,5- tetrahydroxy-5-p-metoxyphenylpentane （1）, （E）-5-（4-methoxyphenyl） pent-4-ene-l,2,3-trihydroxyamyl （2）, isofraxidin （3）, （-）-dihydrodehydrodiconiferyl alcohol （4）, （~）-erythro-guaiacyl-glycerol-^-O-4＇-dihydroconiferyl ether （5）, （-）-rosiridol （6）, （4S）-p-menth-l-ene-4,7-diol （7）, and loliolide （8）, respectively. Conclusion Compounds 1 and 2, named chloranthus pentitol and chloranthus enol, are two newp-methoxyphenyl pentitol derivatives, while compounds 3--8 are obtained from C. angustifolius for the first time.
作者
杜晓英
王璐丰
李有志
丁文兵
DU Xiao-ying WANG Lu-feng LI You-zhi DING Wen-bing(College of Plant Protection, Hunan Agricultural University, Changsha 410128, China College of Agriculture, Yangtze University, Jingzhou 434025, China)
出处
《中草药》
CAS
CSCD
北大核心
2017年第1期42-46,共5页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(31400308)
关键词
狭叶金粟兰
苯基多元醇
单萜
木脂素
金粟兰戊醇
金粟兰烯醇
Chloranthus angustifolius Oliv.
p-phenyl polyol
monoterpenoids
lignans
chloranthus pentitol
chloranthus enol
