摘要
目的探讨新辅助放化疗后经腹腔镜手术对中低位直肠癌的治疗效果。方法将2013年1月至2016年1月本院收治的90例新辅助放化疗后的中低位直肠癌患者随机分为腹腔镜手术组和开腹手术组,每组各45例。腹腔镜手术组患者给予腹腔镜手术治疗,开腹手术组患者给予常规开腹手术治疗。观察并比较两组患者的治疗效果、术后并发症发生情况以及恢复情况。结果腹腔镜手术组患者的淋巴结清扫数目明显多于开腹手术组(P<0.001)、远切端长度显著长于开腹手术组(P<0.001)。腹腔镜手术组患者手术时间明显长于开腹手术组(P<0.001),术中出血量、术后并发症发病率比较均无显著差异(P>0.05)。结论新辅助放化疗后行腹腔镜手术治疗中低位直肠癌,可增加淋巴结清扫数目和远切端长度,具有较好的安全性和可行性。
Objective To investigate the therapeutic effect of laparoscopic surgery after neoadjuvant chemoradiotherapy. Method 90 patients with middle and low rectal cancer from January 2013 to January 2016 were randomly divided into laparoscopic surgery group and laparotomy group, 45 cases in each group. Laparoscopic surgery group patients were treated with laparoscopic surgery, laparotomy group patients received traditional laparotomy for treating, the efficacy, postoperative complications and recovery were observed and recorded. Result The number of lymph node dissection of laparoscopic group was more than laparotomy group （P 〈 0.001）, and distal cut-off length of laparoscopic surgery group were significantly higher than those of laparotomy group （P 〈 0.001）. The operation time of laparoscopic surgery group was significantly longer than that of laparotomy group （P 〈~ 0.001）, but there were no significant difference in the incidence of postoperative complications and amount of bleeding during operation （P 〉 0.05）. Conclusion Lapatoscgpic surgery after neoadjuvant chemoradiotherapy can increase the number of lymph node dissection and distal cut-off length, this method is safe and feasible.
出处
《中国医学前沿杂志（电子版）》
2016年第12期50-53,共4页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
基金
国家自然科学基金(81270456)
关键词
直肠癌
腹腔镜
新辅助放化疗
Rectal cancer
Laparoscope
Neoadjuvant chemoradiotherapy
