摘要
目的探讨节律性视觉刺激对帕金森病患者运动功能及平衡能力的影响。方法选择帕金森病患者89例,随机分为对照组和观察组。对照组给予常规抗帕金森药物进行治疗,观察组除给予常规抗帕金森药物进行治疗外,还给予节律性视觉刺激。比较两组患者运动功能、平衡能力和血清学指标的变化情况。结果观察组患者治疗后10 m步行能力测试(10 mw T)评分、帕金森综合评分量表2(UPDRS-Ⅱ)评分、UPDRS-Ⅲ评分、同型半胱氨酸水平均低于治疗前,步频、步速、步长、6 min步行测试(6 minw T)评分、Berg平衡量表(BBS)评分、血清泌乳素、叶酸水平均高于治疗前,且差异有统计学意义(P<0.05);而对照组治疗各指标差异均无统计学意义(P>0.05);组间比较,训练后,观察组患者运动功能、平衡能力和血清学指标的变化均优于对照组,且差异有统计学意义(P<0.05)。结论通过有效的节律性视觉刺激,可使帕金森患者的运动功能、平衡能力和血清学指标得到显著改善。
Objective To explore the effects of rhythmic visual stimulation on motor function and balance in patients with Parkinson＇s disease. Methods 89 cases of Parkinson＇s disease in our hospital were randomly divided into control group and observation group. The control group was given conventional anti Parkinson drug treatment,the observation group in addition to conventional anti Parkinson drugs were treated,the rhythm of visual stimulation was also given. The changes of motor function,balance ability and serum index were compared between the two groups. Results Observation group patients after training 10 mw T score,UPDRS- Ⅱ score,updrs- Ⅲ score,homocysteine levels were less than training before,stride length and walking speed,step length,6 minw T score,BBS score,serum prolactin,folate levels were higher than before the training,and the difference was statistically significant（P〈0. 05）. Training and observation groups 10 mw T score,UPDRS- Ⅱ score,updrs- Ⅲ score,homocysteine levels were less than the control group,stride length and walking speed,step length,6 minw T score,BBS score,serum prolactin,folate levels were greater than control group,and the difference had statistical significance（P〈0. 05）. Conclusion Through effective visual stimulation,the motor function,balance ability and serological indexes of Parkinson patients were significantly improved.
出处
《临床和实验医学杂志》
2017年第1期55-58,共4页
Journal of Clinical and Experimental Medicine
基金
湖北省卫生与计划生育委员会基金项目(编号:WJ2015Z093)
关键词
帕金森病
节律性视觉刺激
运动功能
平衡能力
血清学指标
Parkinson＇s disease
Rhythmic visual stimulation
Motor function
Balance ability
Serological index
