摘要
目的探讨胃复春对慢性萎缩性胃炎转归的作用及疗程与疗效的相关性。方法选取经内镜确诊的80例慢性萎缩性胃炎患者,将所有患者按照双盲、随机分为两组,A组(对照组)38例接受安慰剂治疗,B组(治疗组)42例接受胃复春治疗,3个月为1个疗程,治疗3个疗程。治疗后3、6、9个月分别进行临床症状评估,行胃镜检查及组织病理检查,比较治疗前后临床表现变化。结果 A组治疗后症状缓解的有效率为23.68%,B组为71.43%,两组比较差异有统计学意义(P<0.05);病理改变、胃镜下检查情况:两组有效率比较差异有统计学意义(P<0.05),使用SPEARMAN秩相关分析,疗效与疗程有明显相关性(P<0.05)。结论胃复春治疗萎缩性胃炎,随疗程的延长疗效增强,3个疗程的治疗可以保证更好的治疗效果。
Objective To investigate the effect of weifuchun capsule on chronic atrophic gastritis and the relationship between the course and the curative effect. Methods Eighty patients with endoscopically confirmed chronic atrophic gastritis were enrolled and randomly divided into two groups,38 cases of group A were treated with placebo,42 cases of group B were treated with wei fuchun capsule,one couse inculded 3 months,totalde for 3 couses. After the treatment of 3,6,9 months,compared the clinical effect of the two groups. Results The effective rate of group A was 23. 68 % and 71. 43% of group B,there showed significantly difference between the two groups( P〈0. 05),endoscopic and histologcial also showded significantly difference( P〈0. 05), according to SPEARMAN rank correlation analysis, there was significant correlation in efficacy and course.Conclusion The treatment of atrophic gastritis with weifuchun,curative effect was obviously enhanced with the extension of curative courses,3 courses of treatment can ensure better curative effect.
出处
《临床医学》
CAS
2016年第11期49-50,共2页
Clinical Medicine
关键词
胃复春
慢性萎缩性胃炎
疗程
疗效
Weifuchun capsule
Chronic atrophic gastritis
Course
Curative effect