摘要
[主要目的]分析慢性肾脏病(CKD5期)经西药抗贫血治疗后肾性贫血程度与辨证分型分布规律。[资料来源]在海门市中医院内科一病区选取2015年6月至2015年12月住院患者。[选择文献量及依据](1)研究类型:回顾性分析。(2)研究对象:符合慢性肾脏病(CKD5期)诊断标准,GFR<15m L/min,中度以上肾性贫血(HGB<90g/L);中医四诊资料齐全;同一患者反复入院症状发生变化时重复纳入,无明显变化时仅纳入第一次入院情况;知情同意,签署知情同意书。(3)评价指标:肾性贫血中分布情况、RBC含量、HGB含量。(4)干预方法:多糖铁,0.15g/次,3次/d,口服;叶酸,5mg/次,3次/d,口服;维生素B12,0.025mg/次,3次/d,口服;EPO,10000iu/周。(5)疗程>6个月。[数据提炼规则及应用方法]统计不同证型肾性贫血程度,采用Excel2010、SPSS17.0统计软件,按证型等分组,统计不同证型肾性贫血不同程度数量,计量资料采用均值±标准差(x±s)表示,计数资料采用χ2检验。[数据综合得出结果与结论]研究发现正虚中阴阳两虚与脾肾阳虚本在贫血情况及HGB、RBC含量中偏低(P<0.05);兼证中湿浊在贫血情况分布及HGB、RBC含量中偏低(P<0.05)。[未来展望]常规治疗慢性肾脏病(CKD5期)肾性贫血疗效存在差异,加用温阳化湿中药或可提高临床疗效,为临床治疗肾性贫血提供新的依据。
[Objectives] Analysis of chronic kidney disease （CKD5 period） after treatment with western medicine for anemia of renal anemia degree and distribution. [Materials source] Selection in haimen traditional Chinese medicine a ward in June 2015 to December 2015 hospitalized patients. [Quantities and criteria] ①Research type： retrospective analysis. ②object of study： In chronic kidney disease （CKD5） diagnostic criteria, GFR〈more than 15 mL/min, moderate renal anemia （HGB〈90 g/L）; TCM four diagnostic data is complete; Repeated the same patients admitted to hospital symptoms change repeat into, no obvious changes include only admitted for the first time; Informed consent, signed informed consent. ③Evaluation： renal anemia in distribution, contents of RBC, HGB.④intervention methods： polysaccharide iron, O. 15 g/time, 3 times/d, oral; Folic acid, 5 mg/ time, 3 times/d, oral; Vitamin B12, 0.025 mg/time, 3 times/d, oral; EPO, 10000 iu/week. （~）Treatment〉6 months. [Data extraction rules and Methods of application] Statistics of different syndrome types of renal anemia, use excel, SPSS17.0 statistical software, according to the type of grouping, statistical different card number in different degree of renal anemia, measurement data using the mean ＋/- standard deviation （N ＋ s）, count data by chi-square test. [The results and Conclusion] Findings are two with spleen and kidney Yang deficiency of Yin and Yang of the virtual in anemia and, RBC, HGB content is low （P〈0.05）; And the dampness in the anemia is distributed and, RBC, HGB content is low （P〈0.05）. [Future prospect] routine treatment of chronic kidney disease （CKD5） renal anemia curative effect difference, plus with this wet or can improve the clinical curative effect, Chinese traditional medicine to provide new basis for clinical treatment of renal anemia.
出处
《实用中医内科杂志》
2016年第12期9-12,共4页
Journal of Practical Traditional Chinese Internal Medicine
基金
2015海门市科技项目(No:2015SSF03)~~
关键词
慢性肾脏病
抗贫血治疗
肾性贫血程度
辨证分型
回顾性分析
chronic kidney disease （CKD）
anemia treatment
degree of renal anemia
syndrome differentiation type
retrospective analysis
