摘要
[主要目的]分析中西医结合治疗恶性肿瘤并发血栓性水肿临床资料。[资料来源]选取辽宁中医药大学附属医院肿瘤科2012年12月到2014年7月住院恶性肿瘤并发血栓性水肿患者。[选择文献量及依据]1研究类型:临床观察。2研究对象:符合恶性肿瘤并发血栓性水肿诊断标准;中医四诊资料齐全;同一患者反复入院症状发生变化时重复纳入,无明显变化时仅纳入第一次入院情况。彩超提示深静脉血栓形成(包括上肢和下肢)。3辨证分型:脾虚湿困、气滞湿阻、气阴两虚、湿热内蕴。4评价指标:有效率、KPS评分等各项指标。5干预方法:西医:低分子肝素皮下注射、华法林,马粟种子提取物、地奥司明。中医:疏血通静点,中药汤剂口服(以柴胡龙牡汤和益气消积汤为主方,加减五苓散),中药外敷(冰硝散、消水方—院内协定方)。排除中医四诊资料不全;治疗过程随意暂停服用药物;病情变化快,48h内迅速并发DIC。共32例住院病历。[数据提炼规则及应用方法]根据干预方法分为中药外敷和未中药外敷。疗效判定:参照《中医病证诊断疗效标准》。使用SPSS15.0软件对疗效进行统计学分析,采用Microsoft Excel 2013软件建立数据库,对KPS评分、生存期、转移部位进行统计。[数据综合得出结果与结论]中药外敷有效率81.25%(13/16),未中药外敷有效率50.00%(8/16),两组间无明显差异(χ2=3.463,P=0.068>0.05)。中药外敷有疗效优势,生存质量评分高、转移部位少。[未来展望]敷药疗法在肿瘤治疗方面及随症加减都需更多的临床数据检验和经验总结,相信未来不仅在恶性肿瘤并发血栓性水肿方面,在更多的临床应用方面,中药外敷法都能发挥积极作用。
[Objective] Combined with the analysis of traditional Chinese and Western medicine treatment of clinical data of malignant tumor patients with thrombotic edema. [Source] Select the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine in 2012 December to 2014 July in Department of oncology hospital in malignant tumor patients with thrombotic edema.[The volume of literature and on the basis] The study type： clinical observation. The object of study： meet the diagnostic criteria of malignant tumor patients with thrombotic edema; TCM diagnostic data is complete; the same in patients with recurrent symptoms during admission changes repeat into,no obvious change when only the first time into the admission condition. Ultrasound in deep venous thrombosis（including upper and lower limbs）. The syndrome differentiation： spleen wet storm,qi stagnation,deficiency of both qi and Yin,damp and hot wet intrinsic resistance. The evaluation index： the index efficiency,KPS score.The intervention method： Western medicine： low molecular weight heparin subcutaneous injection,Hua Falin,horse chestnut seed extract,diosmin. Chinese： Shuxuetong intravenous,oral Decoction of Chinese herbal medicine（to Chai Hu long Mu soup and Yiqi Xiaoji Decoction based parties,plus or minus five Lingya）,external application of Chinese medicine（ice glass powder,by removing water- hospital prescription）. The exclusion of TCM diagnostic data is not complete; the treatment process arbitrarily suspend taking drugs; the condition changes fast,48 h quickly inside the concurrent DIC. A total of 32 cases of hospitalized records.[Data extraction rules and application method] According to the intervention methods are divided into the external application of Chinese medicine and no external applicationof Chinese medicine. Therapeutic efficacy： reference ＂TCM syndrome diagnosis and curative effect standard＂. Statistical analysis was conducted on the effect of the use of SPSS15.0 software,using Microsoft Excel 2013 s
出处
《实用中医内科杂志》
2015年第1期1-3,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
血栓性水肿
恶性肿瘤
股肿
中药外敷
中西医结合
KPS评分
转移情况
循证医学
系统综述
thrombotic edema
malignant tumor
femoral swollen
external application of traditional Chinese medicine
integrated Chinese and western medicine
KPS score
metastasis
evidence based medicine
systematic review
