摘要
目的比较甘精胰岛素与二甲双胍对2型糖尿病(T2DM)患者黎明现象的影响。方法选取我院门诊确诊T2DM黎明现象者65例,随机分为三组:A组单纯甘精胰岛素,共23例;B组单纯二甲双胍,共22例;C组空白对照,共20例。比较三组患者用药前后FBG水平、控制黎明现象发生率。结果三组患者治疗2周后FBG水平均较治疗前明显下降差异有统计学意义(P<0.05),A组控制黎明现象发生率明显下降,差异有统计学意义(P<0.05)。结论甘精胰岛素一种在基层医院值得推广的治疗方法,T2DM患者睡前应用甘精胰岛素可以有效减少黎明现象,具有方便有效且低血糖发生率低的优点。
Objective To compare the effects of insulin glargine and metformin on the dawn phenomenoninpatients with type 2 diabetes mellitus（ T2DM）.Methods 65 cases of outpatient diagnosis of T2 DM dawn phenomenon in our hospital were selected and randomly divided into three groups： group A of simple insulin glargine,a total of 23 cases; group B of metformin alone,a total of 22 cases; group C of blank control,a total of 20 cases. The FBG level and the rate of controlling the occurrence of dawn phenomenon in three groups of patients before and after treatment were compared.Results FBG levels in the three groups after 2w of treatment were significantly lower than those before treatment,and the difference was statistically significant（ P〈0.05）. The rate of controlling the occurrence of dawn phenomenon in group A was significantly decreased,and the difference was statistically significant（ P〈0.05）.Conclusion Insulin glargine is a kind of treatment worthy of promotion in the primary hospital. The use of insulin glarginefor T2 DM patients before going to bed can effectively reduce the dawn phenomenon. And it has the advantages of convenient,effective and low incidence of hypoglycemia.
出处
《四川医学》
CAS
2016年第12期1384-1386,共3页
Sichuan Medical Journal
关键词
2型糖尿病
黎明现象
甘精胰岛素
低血糖
Type 2 diabetes mellitus
dawn phenomenon
insulin glargine
hypoglycemia
