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色素上皮衍生因子、钙黏蛋白、波形蛋白在乳腺浸润性导管癌中的表达及临床意义

Expression of E - cadherin, vimentin and pigment epithelium - derived factor in infiltrating ductal carcinoma and their relationships with prognosis
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摘要 肿瘤细胞的浸润转移是肿瘤患者病死率较高的一个重要原因,上皮一间充质转化(EMT)和癌细胞脱离原发部位在浸润转移过程中起重要作用。色素上皮衍生因子(PEDF)是一个能有效抑制新生血管形成的蛋白,我们通过免疫组织化学方法分析PEDF、上皮细胞钙黏蛋白(E—cadherin)、波形蛋白(Vimentin)的表达,探讨在乳腺癌中表达的相关性及意义。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2016年第12期2808-2809,共2页 Chinese Journal of Experimental Surgery
基金 广东省医学科研基金(B2014395) 佛山市卫生局立项课题(2014197)
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