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右美托咪定复合罗哌卡因用于切口局部浸润对小儿术后镇痛效果的影响 被引量:19

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摘要 目的:探讨右美托咪定复合罗哌卡因用于切口局部浸润在小儿开腹手术后镇痛的安全性和有效性。方法:选择75例择期行全身麻醉下开腹手术的患儿,年龄1~6岁,ASA分级Ⅰ~Ⅱ级,随机分成3组,每组25例,芬太尼组(F组):缝皮时静脉注射芬太尼1μg/kg;罗哌卡因组(R组):0.25%罗哌卡因缝皮前行切口浸润;右美托咪定组(D组):0.25%罗哌卡因+0.25μg/kg右美托咪定缝皮前行切口浸润。观察患儿生命征、FLACC评分、Ramsay评分、术后不良反应。结果:苏醒期躁动的发生率、术后72h内追加镇静、镇痛药物的患儿例数。D组低于F组和R组(P〈0.05)。苏醒期各时点D组的Ramsay评分均高于F组和R组;FLACC评分D组低于R组、F组(P〈0.05)。结论:右美托咪定复合罗哌卡因用于切口局部浸润能为小儿术后24h提供良好的镇痛、镇静.是一种安全、方便、有效的小儿术后镇痛方法。
出处 《实用医学杂志》 CAS 北大核心 2016年第23期3932-3933,共2页 The Journal of Practical Medicine
基金 广西科技厅自然科学基金项目(编号:2011GXNSFA018222) 广西卫生厅自然科学基金项目资助(编号:2014046)
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