摘要
目的探讨高碘中药对妊娠亚甲减患者血清VB12、同型半胱氨酸(Hcy)及甲状腺功能影响研究。方法选取2014年8月-2016年5月于温州市人民医院妇产科以亚甲减为诊断而入院的妊娠期患者84例,随机分为2组。对照组42例,予左甲状腺素钠片治疗;实验组42例,在对照组相同的常规基础治疗外,加用高碘中药治疗。观察2组患者治疗前后血清VB12、Hcy及甲状腺功能水平变化。结果与治疗前比较,2组患者治疗后的血脂、Hcy、促甲状腺激素(thyroid stimulating hormone,TSH)水平均明显降低(P〈0.05),VB12水平均有升高(P〈0.05);治疗后与对照组比较,实验组血脂、Hcy、TSH水平均明显低于对照组(P〈0.05),VB12水平高于对照组(P〈0.05)。结论高碘中药能有效降低妊娠亚甲减患者血脂、Hcy、TSH水平,升高VB12水平,具有较好的临床疗效。
Objective To investigate the effect of high iodine traditional Chinese medicine in the treatment of subclinical hypothyroidism in serum VB12,Hcy and thyroid function. Methods 84 patients of subclinical hypothyroidism from August 2014 to May 2016 in our hospital randomly divided into two groups,the control group of 42 cases were treated with levothyroxine sodium tablets treatment,42 cases in the experimental group received more with high iodine traditional Chinese medicine. The changes of serum VB12,Hcy and thyroid function were observed before and after treatment in two groups.Results Compared with before treatment,levels of blood lipid,Hcy and TSH in two groups significantly decreased,levels of VB12 increased( P〈0. 05);compared with the control group after treatment,levels of blood lipid,Hcy and TSH in experimental group were significantly lower than the control group,the level of VB12 was higher than the control group,the differences were statistically significant( P〈0. 05). Conclusion High iodine can effectively reduce blood lipids in patients with subclinical hypothyroidism,levels of Hcy and TSH in pregnancy,increased the levels of VB12,which has good clinical curative effect.
出处
《中国生化药物杂志》
CAS
2016年第11期163-166,共4页
Chinese Journal of Biochemical Pharmaceutics
关键词
高碘中药
VB12
HCY
甲状腺功能
血脂
high iodine traditional Chinese medicine
VB12
Hcy
thyroid function
blood lipid