摘要
目的通过测定急性脑梗死患者血浆D-二聚体和纤维蛋白原的含量,探讨两者在急性脑梗死发生发展中的临床意义.方法选取85例急性脑梗死患者,按美国国立卫生研究院卒中量表评分（NIHSS）分为轻型组（n=39）,中型组（n=37）,重型组（n=19）;并选取同期85例健康体检者为对照组.所有研究对象均进行血浆D-二聚体和纤维蛋白原水平检测.结果急性脑梗死组与正常对照组比较D-二聚体和纤维蛋白原水平显著升高,并且随着急性脑梗死严重程度的增加,血浆D-二聚体和纤维蛋白原水平逐渐增加,且差异有统计学意义（P〈0.05）.结论观察血浆D-二聚体和纤维蛋白原的水平变化,有利于急性脑梗死的早期诊断,有助于尽早进行干预,在探讨缺血性脑血管病发生发展过程中具有重要的研究价值.
Objective. By measuring the content of plasma D-dimer and fibrinogen in patients with acute cerebral infarction in patients with acute cerebral infarction, explore their clinical significance in the happening and development of acute cerebral infarction. Method. 85 patients with acute cerebral infarction, in compliance with National Institutes of Health Stroke Scale （NIHSS） were divided into light group （n = 39）, medium group （n = 37） and heavy group （n = 19）; at the same, 85 healthy persons were selected as the control group. All the research subjects were tested in plasma D-dimer level and fibrinogen level. Result. Compared with the normal control group, D-dimer level and fibrinogen level in the acute cerebral infarction group were significantly increased, accompanied by the increment of the severity of acute cerebral infarction; and plasma D-dimer and fibrinogen levels increased gradually, which was statistically significant （P 〈 0.05）. Conclusion. The observation of the changes of plasma D-dimer and fibrinogen levels is helpful for the early diagnosis of acute cerebral infarction and conducting intervention as early as possible, which is importantly valued in the research of the happening and development of acute cerebral infarction.
出处
《湖南中医药大学学报》
CAS
2016年第A02期659-660,共2页
Journal of Hunan University of Chinese Medicine
