摘要
癫痫严重影响母胎结局,增加围产期发病率及母胎死亡率,而抗癫痫药物的使用增加胎儿先天畸形发生率。为此,合理使用抗癫痫药物是妊娠合并癫痫管理的关键。应注意尽可能单一用药,避免使用丙戊酸钠及苯妥英钠,以最低有效剂量控制癫痫发作,规律检测血药浓度,适时调整剂量。
Epilepsy affects the pregnant outcome, increases perinatal morbidity and mortality. Meanwhile antiepileptic drugs increase the prevalence of congenital malformation. Appropriate antiepileptic drugs are the key point of management for epilepsy in pregnancy. Pay attention to the treatment of epilepsy in pregnancy, such as single drug, avoiding using valproate and phenobarbital, minimum effective drug dose, monitoring serum antiepilepticdrugs level regularly and making adjustment timely.
出处
《中华产科急救电子杂志》
2016年第2期102-106,共5页
Chinese Journal of Obstetric Emergency（Electronic Edition）
关键词
妊娠
高危
癫痫
抗惊厥药
先天畸形
Pregnancy, high-risk
Epilepsy
Anticonvulsants
Congenital abnormalities
