摘要
目的研究减压提取工艺条件下水和不同体积分数乙醇沸点、饱和蒸气压的相关性,并比较不同药材(穿心莲、红花、白芷、钩藤、黄芩、丹参、陈皮)的加入和不同粒径药材的加入对饱和蒸气压的影响。方法采用理论计算和仪器实验测定结合方法,获取不同沸点下和饱和蒸气压的理论值及实测值,并进行统计分析。结果得到饱和蒸气压与溶剂乙醇体积分数和沸点之间的回归方程P=76.467 1+0.035 2 T2+1.201 0TV-30.749 4V2-3.123 9T-14.966 7V;实验条件下,水和不同体积分数乙醇纯溶剂饱和蒸气压理论值较实测值小;加入药材后饱和蒸气压实测值比纯溶剂实测值增大;药材粉碎后,提取温度达到一定温度后饱和蒸气压会降低。结论药材的加入和粉碎对溶剂饱和蒸气压有影响,但其变化范围小。
Objective To investigate the correlation of water and different volume fractions of ethanol boiling point and saturated steam pressure when using the vacuum extraction technology,and to compare the impact on saturation steam pressure of the addition of different medicine materials （Andrographis paniculata,Carthamus tinctorius,Angelica dahurica,Uncaria rhynchophylla,Scutellaria baicalensis,Salvia miltiorrhiza,Citrus reticulata） or the addition of materials with different particle sizes.Methods To obtain the theoretical value and measured value of saturated steam pressure under different boiling points by the combined method of theoretical calculation,experiment measurement,and statistical analysis Results The regression equation for the saturated steam pressure （P） with the volume fraction of ethanol solvent （V） and the boiling point （T） was P=76.467 1＋0.035 2 T2＋1.201 0 TV-30.749 4 V2-3.123 9 T-14.966 7 V.The results showed that measured values of the saturated steam pressure of pure solvent,water and different concentration of ethanol,was less than the theoretical value.After adding herbs,the measured value of saturated steam pressure was higher than the pure solvent.The saturated steam pressure would reduce exactly as the extraction temperature reaches a certain temperature after the herbs were added.Conclusion The addition and crush of herbs have influence on the saturated vapor pressure of solvent with small range.
出处
《中草药》
CAS
CSCD
北大核心
2016年第23期4166-4172,共7页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金项目(81173565
81560657)
江西省青年科学基金项目(20161BAB215211)
江西省重点研发计划项目(20161BBG70073)
关键词
减压提取
沸点
饱和蒸气压
回归分析
相关性
穿心莲
红花
白芷
钩藤
黄芩
丹参
陈皮
vacuum extraction technology
boiling point
saturated steam pressure
regression analysis
Andrographis paniculata（Burm. f.） Nees
Carthamus tinctorius L.
Angelica dahurica （Fisch. ex Hoffm.） Benth. et Hook. f.
Uncaria rhynchophylla （Miq.）Miq. ex Havil.
Scutellaria baicalensis Georgi
Salvia miltiorrhiza Bge.
Citrus reticulata Blanco
