摘要
目的：探讨矮身材患儿的病因构成，为临床诊断治疗提供参考依据。方法回顾性分析176例矮身材患儿的临床资料。结果176例矮身材患儿中男童102例（58．0％），平均年龄（（9．05±3．28）岁；女童74例（42．0％），平均年龄（8．53±2．76）岁；原发性生长激素缺乏症84例（47．7％）；特发性矮小27例（15．4％）；体质性青春发育延迟16例（9．1％）；家族性矮身材12例（6．8％）；甲状腺功能减低4例（2．3％）；多种垂体激素缺乏症1例（0．6％）；小于胎龄儿4例（2．3％）；染色体疾病10例（5．7％）（其中 turner 综合征6例，其他染色体异常4例）；颅内肿瘤8例（4．5％）（其中包括颅咽管瘤术后继发多种垂体激素缺乏症3例，生殖细胞瘤放疗术后继发多种垂体激素缺乏症1例，垂体腺瘤4例）；垂体柄中断2例（1．1％），Rathkes 囊肿2例（1．1％）；黏多糖病1例（0．6％），Prader-Willi 综合征2例（1．1％）；慢性系统性疾病3例（1．8％）（包括先天性心脏病、慢性肾功能衰竭、幼年特发性关节炎各1例）。结论生长激素缺乏症是矮身材最常见病因。但儿童矮身材病因复杂，需根据不同病因选择治疗方案。
Objective To investigate the causes of short stature in children,and to provide reference for clinical diagnosis and treatment.Methods Anthropological and physical examination data were retrospectively collected and studied in 176 children with short stature.Results Among the 176 children,102 children were males [mean age was （9.05 ±3.28）years old]and 74 children were females[mean age was （8.53 ±2.76）years old].Of them,84cases（47.7%）were diagnosed growth hormone deficiency（GHD）,27cases（15.4%）were idiopathic short stature,16cases（9.1%）were constitutional delay of growth and puberty,12cases（6.8%）were familial short stature, 4cases（2.3%）were hypothyroidism,1case （0.6%）was multiple pituitary hormone deficiency,4cases（2.3%）were small for gestational age （SGA）,10cases（5.7%）were chromosomal disorders,etc.Conclusion GHD is the most common cause of short stature.The causes of short stature are complicated in children.The diagnosis and treatment should be based on etiology.
出处
《中国基层医药》
CAS
2016年第23期3526-3530,共5页
Chinese Journal of Primary Medicine and Pharmacy
关键词
矮身材
病因学
儿童
Short stature
Etiology
Child
