摘要
目的分析鼻咽癌患者的预后及死亡原因。方法回顾性分析196例鼻咽癌患者的临床资料,分析影响鼻咽癌患者预后的相关因素。结果 196例患者的5年生存率和无进展生存率分别为71.9%和65.8%。死亡55例;其中,鼻咽癌相关死亡39例(70.9%),治疗并发症引起的死亡4例(7.3%),其他肿瘤导致的死亡5例(9.1%),心脑血管疾病死亡6例(10.9%),不明原因猝死1例(1.8%)。伴有远处转移患者肿瘤相关病死率高于单纯局部复发患者(P<0.01)。年龄和临床分期是影响鼻咽癌患者5年生存率的独立预后因素(P<0.05)。结论鼻咽癌复发及转移是导致患者死亡的主要原因,高龄和临床分期较晚是临床预后不良因素。
Objective To investigate the prognosis and causes of death in the patients with nasopharyngeal carcinoma. Methods The clinical d4ta of 196 patients with nasopharyngeal carcinoma were reviewed. The factors related to the prognosis were analyzed. Results The rates of 5-year survival and progression-free survival were 75.5 % and 65. 8%, respectively. Of 55 dead patients, the causes of death were nasopharyngeal carcinoma-related recurrence and metastasis in 39 cases （70. 9%）, treatment-related complications in 4 cases （7.3%）, other tumors in 5 cases （9. 1%）, cardiovascular disease in 6 cases（10. 9%） and unidentified sudden death in 1 case（1.8%）. The tumor related mortality in the patients with distant metastasis was higher than that in those with local recurrence（P〈0. 01）. The age and clinical stage were the independent prognostic factors of survival time in the patients with nasopharyngeal carcinoma （P〈0. 05 ）. Conclusion The recurrence and metastasis of nasopharyngeal carcinoma are the major causes of death. The old age and advanced clinical stage are the factors for the poor prognosis of the patients with nasopharyngeal carcinoma.
出处
《江苏医药》
CAS
2016年第21期2353-2355,共3页
Jiangsu Medical Journal
关键词
鼻咽癌
Nasopharyngeal carcinoma
