摘要
目的 通过体检调查,对非酒精性脂肪肝危险因素进行对照分析,为防治及医疗决策提供依据。方法 收集2014年7月~2016年1月于笔者所在医院进行常规体检的1004人完整资料,根据是否患有NAFLD,将患者分为病例组295例与对照组709例两组。采用问卷调查与健康体检两部分收集调查对象的年龄、性别、职业、既往病史等一般特征及NAFLD临床诊断。对比分析两组研究对象BMI、收缩压、舒张压、PBG、TG、TC、ALT与UA水平。结果 在1004例研究对象中,共检出NAFLD 295人,其发生率为29.38%。两组研究对象在年龄、空腹血糖差异无统计学意义（P〉0.05）。病例组患者BMI、收缩压、舒张压、PBG、TG、TC、ALT与UA水平,均明显高于对照组,差异显著具有统计学意义（P〈0.05）。以NAFLD为应变量,性别、年龄、BMI、空腹血糖、舒张压、胆固醇、甘油三酯和丙氨酸氨基转移酶为自变量进行Logistic回归分析,脂肪肝危险因素依次为甘油三酯、胆固醇、空腹血糖、BMI、舒张压、ALT、年龄和男性。结论 烟台地区NAFLD患病率较高,高脂血症、超重及肥胖、糖尿病、高血压、高丙氨酸转氨酶、年龄、男性等为非酒精性脂肪肝的危险因素。合理控制体重,适当锻炼,做好高血压、糖尿病、肥胖的控制,可积极预防NAFLD的发生。
Objective To analyze the risk factors of nonalcoholic fatty liver disease by physical examination survey, and to provide evidence for the prevention and treatment of the disease. Methods The complete data of 1004 people who were in the author＇s Hospital for routine medical examination from July 2014 to January 2016, was collected. According to whether or not suffering from NAFLD, the patients were divided into the case group of 295 cases and the control group of 709 cases. The age, sex, occupation, past medical history and other general characteristics of the subjects were collected by questionnaire survey and health examination in the two parts. The levels of BMI, systolic blood pressure, diastolic blood pressure, PBG, TG, TC, ALT, UA of the two groups were compared and analyzed. Result In 1004 cases of the study, a total of 295 NAFLD were detected, the incidence was 29.38%. There was no significant difference in age and fasting blood glucose between the two groups （P 〉 0.05）. The levels of BMI, systolic blood pressure, diastolic blood pressure, PBG, TG, TC, ALT and UA of the patients group were significantly higher than that of the control group, and the differences were statistically significant（P 〈 0.05）. L_ogistic regression analysis was performed with NAFLD as the dependent variable, sex, age, BMI, fasting blood glucose, diastolic blood pressure, cholesterol, triglyceride and alanine aminotransferase as the independent variables. The risk factors of fatty liver were triglyceride, cholesterol, fasting blood glucose, BMI, diastolic blood pressure, ALT, age and male. Conclusion The prevalence rate of NAFLD was higher in Yantai area. Risk factors for nonalcoholic fatty liver disease, such as hyperlipidemia, overweight and obesity, diabetes mellitus, hypertension, high alanine aminotransferase, age, male and so on. Reasonable weight control, proper exercise, do a good job in hypertension, diabetes, obesity control, can actively prevent the occurrence of NAFLD.
出处
《中国医药科学》
2016年第16期147-149,共3页
China Medicine And Pharmacy
关键词
非酒精性脂肪肝
危险因素
体检
Nonalcoholic fatty liver
Risk factors
Physical examination
