摘要
目的:在确定金银花、连翘及其配伍后抗多药耐药耐甲氧西林金黄色葡萄球菌(MDR-MRSA)的基础上,探讨金银花、连翘及二者配伍后对临床常见的11种致病菌的作用。方法:将金银花、连翘及其配伍后抗多药耐药耐甲氧西林金黄色葡萄球菌(MDR-MRSA)的最优活性组分,分别采用微量稀释法进行体外抗菌实验。结果:金银花、连翘配伍使用后对11种菌均具有抑菌和杀菌作用,其作用优于单味药和双黄连粉针剂。结论:金银花、连翘配伍不仅对MDR-MRSA具有抗菌作用,对临床分离的11种致病菌依然具有抗菌作用,可为临床抗感染治疗提供用药基础。
Objective ： On the basis of anti - MDR - MRSA, to and the compatibility of two herbs on 11 kinds of clinical study the anti - bacterial effect of honeysuckle, forsythia pathogenic bacteria. Methods ： The antibacterial effect of honey- suckle, forsythia and its compatibility was studied in vitro antibacterial experiment by using micro - dilution method. Re- suits ： Honeysuckle, forsythia and its compatibility had the bactericidal effect on 11 kinds of clinical bacteria. The effect of compatibility was better than the single herb and Shuanghuanglian injection. Conclusion：The compatibility of honey- suckle and forsythia has an antibacterial effect not only on MDR - MRSA, but also on 11 kinds of clinical pathogenic bacteria. It can provide a basis for the clinically anti - infective drug therapy.
出处
《中医药学报》
CAS
2016年第5期43-47,共5页
Acta Chinese Medicine and Pharmacology
基金
中国博士后科学基金面上资助(2013M541426)
黑龙江省博士后资助(LBH-Z12263)
黑龙江省教育厅科学技术研究项目(12541762)
关键词
临床致病菌
MDR-MRSA
金银花
连翘
配伍
Clinical pathogens
MDR - MRSA
Honeysuckle
Forsythia suspensa
Compatibility
