摘要
目的探索两种胚胎移植管对全胚冷冻后首次胚胎移植的患者临床妊娠结局的影响。方法回顾性分析行全胚冷冻后首次冻融移植周期,依据使用的移植管分成两组,A组采用COOK-K-JETS-7019-SIVF移植管(200个周期);B组采用Edwarda-Wallace移植管(242个周期),观察并比较两组患者的一般情况及妊娠结局。结果两组在对应取卵周期的年龄、BMI、血清bE_2、bFSH、bLH、Gn使用量和使用时间、HCG日LH、HCG日E_2、获卵数、总受精数、优质胚胎数、移植日内膜厚度及移植胚胎数目之间的差异均无统计学意义(P>0.05);A组的胚胎种植率、临床妊娠率均高于B组,差异有统计学意义(P<0.01)。结论质地柔软、顺应性较好的胚胎移植管可以获得更好的妊娠结局。
Objective To explore the influence of two different soft catheters on the pregnancy outcomes in the first frozen thawed embryo transfer cycle after all - embryo - freezing. Methods A retrospective analysis was performed on patients who underwent the first frozen thawed embryo transfer cycle between February 2013 and November 2015, in Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical Univer- sity. They were divided into two groups： Group A, using COOK -K -JETS -7019 -SIVF （n = 200 cycles）, and Group B group, using Edwarda - Wallace （ n = 242 cycles）. The basic characteristics and the pregnancy outcomes were com- pared. Results A total of 442 cycles were enrolled in this study. There were no significant differences in age, BMI, bas- ic E2, FSH, LH, total gonadotropin dosage, days of stimulation, the levels of E2 and LH at HCG injection of the corre- sponding ooctye retrieval cycle, number of ooeytes collected, or number of oocytes fertilized and number of good - quality embryos in the corresponding ooctye retrieval cycle （ P 〉 0. 05 ）. There was no significant difference in endometrial thick- ness and the number of embryos transferred between two groups either （ P 〉 0. 05 ）. However, the implantation rate and clinical pregnancy rate in Group A were significantly higher than those in Group B （P 〈 0. 001 ）. Conclusion Using soft catheter might lessen the difficulty during the frozen thawed embryo transfer cycle and improve the pregnancy outcomes.
出处
《广东医学》
CAS
北大核心
2016年第19期2886-2888,共3页
Guangdong Medical Journal
基金
国家自然科学基金资助项目(编号:81170574,81401177)
广东省自然科学基金资助项目(编号:2015A030313286)
关键词
全胚冷冻
胚胎移植管
冻融胚胎移植
临床妊娠率
all -embryo- freezing
catheter
frozen thawed embryo transfer
clinically pregnancy rate
