摘要
目的:观察分析加味消髓化核汤联合西医治疗根性坐骨神经痛的临床疗效。方法:300例根性坐骨神经痛患者随机分为观察组和对照组各150例。对照组给予奥卡西平片、甲钴胺片、泼尼松片,结合腰椎三维牵引治疗;观察组在对照组基础上加用加味消髓化核汤。两组疗程均为3周。比较两组临床疗效、VAS疼痛评分和神经传导速度,记录药品不良反应。结果:观察组总有效率为91.33%,明显高于对照组的78.67%(P<0.01)。两组治疗后VAS疼痛评分以及运动神经传导传速度(MCV)、感觉神经传导速度(SCV)等各指标均较治疗前显著改善(P<0.05),且观察组的各项指标明显优于对照组(P<0.05)。两组药品不良反应发生率相近(P>0.05)。结论:加味消髓化核汤联合西医治疗根性坐骨神经痛临床疗效肯定,值得临床推广运用。
Objective： To observe the efficacy of Jiaweixiaosuihuahe decoction combined with western medicines for the therapy of sciatica of nerve roots. Methods： A total of 300 patients with sciatica of nerve roots were randomly divided into the study group （ 150 cases） and the control group （150 cases）. The control group received oxcarbazepine, mecobalamin, prednisone and three-dimensional lumbar traction, and the study group was treated with Jiaweixiaosuihuahe decoction additionally. The treatment course was 3 weeks. The clinical effects, VAS score and nerve conduction velocity were compared, and the adverse reactions were recorded. Results： The total effective rate （91.33%） of the study group was higher than that （78.67%） of the control group （P 〈 0.01 ）. After the treat- ment, the VAS score, motor nerve conduction velocity （MCV） and sensory nerve conduction velocity （SCV） were improved in both groups （P 〈 0.05 ）, and compared with those in the control group, the improvement in the study group was more notable （P 〈 0.05 ）. The incidence of adverse reactions in the two groups was similar（ P〉0.05 ）. Conclusion： Jiaweixiaosuihuahe decoction combined with western medicines is an effective method for the therapy of sciatica of nerve roots, which is worthy of wide clinical use.
出处
《中国药师》
CAS
2016年第11期2083-2085,共3页
China Pharmacist
关键词
根性坐骨神经痛
中西医结合
加味消髓化核汤
疗效
Sciatica of nerve roots
Integration of traditional Chinese and western medicines
Jiaweixiaosuihuahe decoction
Efficacy
