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急性脑梗死患者血清神经元特异性烯醇化酶和S100β含量与核磁弥散加权成像的对比 被引量:9

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摘要 目的 探讨神经元特异性烯醇化酶(NSE)和S100β蛋白水平在急性脑梗死临床应用中的可行性。方法 选取2012-2014年在北华大学附属医院神经内科住院,符合急性脑梗死的诊断标准、发病在24 h内的78例患者,根据梗死面积分为小、中、大梗死组,行头部核磁弥散加权成像(MR-DWI)检查及血清NSE、S100β蛋白检测。对照组为我院健康体检人员40例。结果 两组血清NSE、S100β蛋白水平有统计学差异(P〈0.001)。核磁弥散病灶大小与血清NSE、S100β水平均呈正相关(r=0.851,0.758;P〈0.05)。结论 急性脑梗死患者血清NSE、S100β水平的变化能反映脑组织损伤的严重程度,可以作为急性脑梗死患者病情评估的一项重要指标,较影像学检查更方便、更经济、易于掌握。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第20期5015-5016,共2页 Chinese Journal of Gerontology
基金 吉林省卫生厅课题(20132095)
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参考文献11

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