摘要
目的：探讨磁共振弥散张量成像及纤维束成像在脑胶质瘤分级中的意义及对于临床术前制定手术方案的应用价值。方法：搜集2014-05~2015-06在佳木斯大学附属第一医院诊断并得到病理证实的脑胶质瘤患者资料共42例,按高低不同级别分为两组,分别进行常规MRI检查及DTI检查,经后处理后得到FA值及相应DTT图。采用t检验对数据进行统计学分析,P〈0.05为有统计学意义。结果：1高级别胶质瘤肿瘤实体区比低级别胶质瘤肿瘤实体区的FA值小（P〈0.05）;2高级别胶质瘤瘤周水肿区比低级别胶质瘤瘤周水肿区的FA值小（P〈0.05）;3同一肿瘤的肿瘤实体区比瘤周水肿区的FA值小（P〈0.05）。4低级别胶质瘤周围白质纤维束主要表现为正常或移位,高级别胶质瘤周围白质纤维束主要表现为稀疏或中断。结论：FA值能够用来区分高低级别胶质瘤,而DTT图则能够为临床术前手术区域的划分提供帮助。
Objective： To discuss the value of diffusion tensor imaging and diffusion tensor tractography in cerebral gliomas diagnostic classification,and its application value of preoperative formulation for clinical operation.Methods： 42 patients with brain glioma who were diagnosed and confirmed pathologically in the First Affiliated Hospital of Jiamusi University from May 2014 to June 2015 were collected. According to different grades,these patients were divided into two groups. The routine MRI examination and DTI examination were performed respectively on them. The values of FA and the corresponding DTT figure after processing were available. The data was statistically analyzed by test. Assuming that P〈0. 05 was statistically significant. Result：（ 1） The FA values of the solid area of high grade gliomas is lower than that of the low grade gliomas（ P〈0. 05）.（ 2） The FA values of the peripheral edema area of high grade gliomas is lower than that of the low grade gliomas（ P〈0. 05）.（ 3） The FA values of the solid area in the same tumor is smaller than that of the peripheral edema area（ P〈0. 05）.（ 4） The white matter features around the low grade gliomas are normal or shift. And that which around the high grade gliomas are sparse or interrupted. Conclusion： The values of FA can be used to distinguish between high and low grade gliomas. And the DTT figure can provide help to preoperative division of operation area for clinicians.
出处
《黑龙江医药科学》
2016年第5期63-65,共3页
Heilongjiang Medicine and Pharmacy
