摘要
目的观察清利肝胆活血化瘀中药联合西药治疗婴儿巨细胞病毒性肝炎(湿热内蕴证)的临床疗效。方法将60例患儿按随机数字表法分为治疗组40例和对照组20例。对照组给予注射更昔洛韦同时给予注射维生素C、肝水解肽等保肝对症治疗。治疗组在对照组的基础上给予口服清利肝胆活血化瘀中药汤剂。两组疗程均为2周。观察皮肤、巩膜黄染情况,大小便颜色变化,肝脾大小质地变化及肝功能变化。结果治疗组临床疗效愈显率为70.00%,总有效率为92.50%;对照组分别为30.00%和75.00%,两组临床疗效比较差异有统计学意义(P<0.05),治疗组优于对照组。结论清利肝胆活血化瘀中药联合西药治疗婴儿巨细胞病毒性肝炎湿热内蕴证临床疗效优于单纯西药治疗,可明显改善患儿临床症状、体征和肝功能。
Objective： To observe the clinical effect of traditional Chinese medicine combined with western medicine in the treatment of infantile cytomegalovirus hepatitis with syndrome of damp heat accumulating inside. Methods： A total of 60 children with infantile cytomegalovirus hepatitis of damp heat accumulating syndrome were randomly divided into treatment group （40 cases） and control group （20 cases）.The control group received ganciclovir injection 5 mg/（kg times）,intravenous drip per 12 h 1 times ;while being given injections of vitamin C ,Heparolysate liver protection treatment etc. Additionally,the treatment group orally took decoction of ciearing heat, promoting dieresis,invigorating the circulation of blood and removing toxin, 1 dose daily. The course of treatment was both 2 weeks. The change of skin ,yellow sclera ,urine color,the size and texture of liver and spleen and liver function was observed. Results： In the treatment group ,the remarkably effective rate was 70% ,the total effective rate was 92.5% ,while that was 30% and 75% respectively in the control group. The difference between the groups was statistically significant （P〈 0.05）. Conclusion： The efficacy of clearing heat,promoting dieresis, invigorating the circulation of blood and removing toxin combined with western medicine for infantile cytomegalovirus hepatitis with syndrome of damp heat accumulating inside is superior to the treatment of using western medicine only.
作者
穆静
杨燕
刘畅
MU ling YANG Yan LIU Chang(Beijing Children＇s Hospital, Capital Medical University ,Beijing 100045, China)
出处
《中国中医急症》
2016年第10期1932-1934,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
国家自然科学基金项目(81473725)
北京市中医药科技项目(JJ2014-45)
关键词
婴儿巨细胞病毒性肝炎
中药
湿热内蕴证
Infant cytomegalovirus hepatitis
Traditional Chinese medicine
Syndrome of damp heat accumulat- ing inside
