摘要
报道我院１４年来诊断为婴儿肝炎综合征（婴肝）住院并死亡的５１例病儿。为探讨婴肝患者的肝脏病理改变与死亡的关系，我们对全部病儿进行尸检，并根据肝脏病理变化分以下几型：①重症肝炎：（急性及亚急性）２８例（５４．９０％）；②急性肝炎：９例（１７．６５％）；③巨细胞病毒肝炎（ＣＭＶ）：３例（５．８８％）；④慢性活动性肝炎（ＣＡＨ）：２例（３．９２％）；⑤胆道闭锁及胆汁性肝硬变：９例（１７．６５％）。根据上述病理改变明确了婴肝患儿肝脏病变的病因，与国内１９９１年林氏报道相比，更多了ＣＭＶ及ＣＡＨ两型病变，对临床为降低婴肝病死率，在诊治该类病儿时具进一步的参考及指导意义。
This article is to report the pathological findings of infantile hepatitis syndrome obtained from autopsy during the period of Jan. 1975～Dec.1988.The mortality rate was 7.12%,accounting for 4.3% of the total autopsies during the same period.Of all the 51 cases,31 were males and 20-females.45 of them were under the age of 6 months,accounting for 88.3%.According to the pathological changes of the liver,the pathological findings may be classified as follows:1.Fulminant hepatitis,acute or subacute: 28 cases,accounting for 54.90%.2.Acute hepatitis:9 cases,17.65%.3.Cytomegaloviral hepatitis:3 cases,5.85%.4.Chronic active hepatitis:2 cases,3.92%.5.Biliary atresia and biliary cirrhosis:9 cases,accounting for 17.65%.47 cases in this group had clinical complications,accounting for 92.16%.Most of the complications were pneumonia and septicemia.In the process of autopsy,pneumonia was found in 44 cases,accounting for 86.12%,13 of them had pulmonary hemorrhage.19 of them had changes in thymus,accounting for 37.25%.3 cases were found to have the viscerl fungi infection.Although 40 of the 51 cases died of their primary disease,the various complicatinos were also an important cause of death.
出处
《上海医科大学学报》
CSCD
1994年第3期212-215,共4页
Journal of Fudan University(Medical Science)
关键词
婴儿
肝炎综合征
尸体解剖
病理
hepatitis syndrome of infancy
autopsy
pathological observation
