摘要
回顾了有关肥大细胞与针灸的研究历史起源,介绍了1977年宋继美提出的皮肤肥大细胞与经穴现象相关的假说,该学说首次提出肥大细胞是经穴"感传"和"得气"现象的细胞学基础。后经多个研究机构的独立实验验证,目前已有足够证据表明"宋氏理论"(Song’s Theory)的科学性,及其对针灸基础研究和临床实践的潜在重要价值。最近的研究发现皮肤肥大细胞可能接受中枢信号和穴区刺激双向控制,具有交互调节作用,可产生"敏化"现象。本文简述了近40年的研究证据,指出了肥大细胞系统同"经穴现象"相关的15个生物特征,同时提出了明确肥大细胞在人体皮肤的分布及其与经络和穴位的整体关系等10个未来研究需要回答的关键问题和探索方向。
The historical origin of researches regarding acupuncture and mast cells（MCs）is reviewed,and the hypothesis that dermal MCs might be correlated with the acupuncture phenomena proposed by SONG Jimei in1977 is introduced.This hypothesis,for the first time,suggests MCs could be the cellular basis of meridian sensation and arrival of qi（deqi）of acupoints.With independent tests of several research institutes,currently sufficient evidences prove the scientific values of SONG＇s theory as well as its potential values for the basic research and clinical practice of acupuncture.It is reported recently that MCs might receive signals from central nerve system and acupoint stimulation,showing cross-talk effects,therefore,MCs can be sensitized at acupoints.In this paper,with a review of 40-year research evidence,15 biological characteristics regarding mast cells and acupuncture phenomena are identified,in the meanwhile,10 key questions and research direction,including the distribution of MCs in skin and its general relationship with meridian-acupoint,etc.are proposed.
出处
《中国针灸》
CAS
CSCD
北大核心
2016年第10期1063-1068,共6页
Chinese Acupuncture & Moxibustion
关键词
经络
穴位
肥大细胞
针刺
经络实质
宋氏理论
meridian
acupoint
mast cells（MCs）
acupuncture
meridian essence
SONG＇s theory
