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血清骨膜蛋白在毛细支气管炎中的临床意义 被引量:3

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摘要 目的:探讨血清骨膜蛋白在毛细支气管炎中的临床意义。方法选择2013年9月至2014年5月在无锡市儿童医院呼吸内科及外科住院的176例患儿作为研究对象,其中毛细支气管炎组85例(轻度毛支组40例、重度毛支组45例);普通肺炎组44例及对照组47例。分别检测患儿外周血嗜酸粒细胞比例,ELISA法检测血清总IgE和骨膜蛋白浓度,并进行统计学分析。结果轻度毛细支气管炎组、重度毛细支气管炎组及普通肺炎组、对照组四组血清骨膜蛋白浓度比较差异有统计学意义(H=45.8053,P〈0.0001);轻度毛细支气管炎组较重度毛细支气管炎组高(χ^2=8.31,P〈0.05)。轻度毛细支气管炎组、重度毛细支气管炎组、普通肺炎组及对照组四组嗜酸粒细胞百分数差异无统计学意义(H=3.8710,P =0.2757);四组间血清IgE浓度差异无统计学意义(H=1.1088,P=0.7750)。结论毛细支气管炎气道存在嗜酸性粒细胞炎症,骨膜蛋白是毛细支气管炎气道嗜酸性粒细胞炎症的一项重要预测指标。
出处 《国际儿科学杂志》 2016年第9期726-728,共3页 International Journal of Pediatrics
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参考文献15

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