摘要
目的了解北京市房山区腹泻患者的病原谱情况,为肠道传染病的防治工作提供依据。方法在房山区2家二级医院收集未用抗生素的腹泻患者肛拭子和粪便标本,进行志贺菌、沙门菌、副溶血弧菌、5种致泻性大肠埃希菌及轮状病毒和诺如病毒的分离培养和鉴定。结果共收集377例腹泻患者的标本,其中男性217例,女性160例;20~39岁患者占56.23%。检出肠道致病菌58株,检出率为15.38%。其中副溶血弧菌24株（41.38%）;致泻性大肠杆菌19株（32.76%）,包括肠毒性大肠杆菌（ETEC）12株,肠致病性大肠杆菌（EPEC）5株,肠粘附性大肠杆菌（EAEC）2株;沙门菌14株（24.2%）,优势血清型为肠炎沙门菌。检出肠道腹泻病毒42株（11.14%）,其中诺如病毒GII型最多,30株。职业分布居于前3位的为：干部职员30例（31.25%）,学生11例（11.46%）,家务及待业11例（11.46%）。腹泻致病菌检出时间主要分布于夏秋季,检出高峰为6—9月。腹泻病毒检出高峰为3—5月。结论房山区腹泻患者病原菌种类多,应在继续加强监测的同时开展宣传教育。
[Objective]To understand enteric pathogenic spectrum of diarrhea patients in Fangshan District of Beijing,provide the basis for prevention and control of intestinal infectious diseases.[Methods]Anal swabs and stool samples were collected from diarrhea patients who were not treated with antibiotics in two grade-2 hospitals,to isolate and culture the Shigella,Salmonella, Vibrio parahaemolyticus, 5 kinds of pathogenic Escherich ia coli, rotavirus and norovirus.[Results]Totall y377 diarrhea patients were investigated,including 217 male patients and 160 female patients. 56.23% of patients were people aged 20-39 years old. 58 strains of enteric pathogenic bacteria were detected with the detection rate of 15.38%,including24（41.38%）strains of Vibrio parahaemolyticus,19（32.76%）strains of Diarrhea genie Escherichia coli（12 strains of ETEC,5 strains of EPEC and 2 strains of EAEC）,14（24.2%） strains of Salmonella,which the dominant serotypes of Salmonella enteritidis. There were 42（11.14%） strains of intestinal diarrhea virus,and 30 strains were GII norovirus. The occupational distribution showed that top three occupations were cadre staff（30 cases,31.25%）,students（11 cases,11.46%）,housework and unemployment（11 cases,11.46%）. Most of enteric pathogenic bacteria were detected in summer autumn,which the peak season appeared June to September,and the peak season of intestinal diarrhea virus appeared March to May.[Conclusion]The pathogenic bacteria of diarrhea patients are diverse in Fangshan District. It is necessary to strengthen the monitoring and improve the publicity and education.
出处
《职业与健康》
CAS
2016年第17期2420-2422,共3页
Occupation and Health
关键词
腹泻
致泻大肠埃希菌
副溶血弧菌
沙门菌
Diarrhea
Diarrhea genie Escherichia coli
Vibrio parahaemolyticus
Salmonella
