摘要
目的:探究加替沙星与左氧氟沙星治疗细菌性结膜炎的疗效,并将其进行对比分析。方法:选取2014年11月至2015年11月在南昌市第三医院门诊部就诊的90例细菌性结膜炎患者为研究对象,将其按照不同的治疗方法分成两组,即对照组和研究组,各45例。对照组给予左氧氟沙星进行治疗,研究组给予加替沙星进行治疗,观察两组患者的治疗效果、治愈所用时间、细菌清除情况以及不良反应发生情况。结果:对照组的总有效率为82.22%,研究组的总有效率为95.56%,研究组患者的总有效率高于对照组,差异存在统计学意义(P<0.05);对照组患者治愈所用时间为(8.21±1.06)d,研究组治愈所用时间为(6.15±1.05)d,与对照组相比,研究组患者治愈所用时间明显较短,数据存在统计学意义(P<0.05);对照组的细菌清除率为77.78%,研究组的细菌清除率为93.33%,两组患者细菌清除率差异较大,数据存在统计学意义(P<0.05);对照组的不良反应发生率为8.89%,研究组的不良反应发生率为6.67%,两组患者不良反应发生率均较低,差异不存在统计学意义(P>0.05)。结论:左氧氟沙星治疗细菌性结膜炎效果更优,值得推广应用。
Objective： To explore curative effect of gatifloxacin and levofloxacin in the treatment of bacterial conjunctivitis. Methods： 90 cases of bacterial conjunctivitis patients from November 2014 to November 2015 in our hospital outpatient were divided into two groups, namely the control group and the research group, each of 45 cases. The control group was treated with levofloxacin, while the study group was treated with gatifloxacin, and treatment effect, cure time, bacterial clearance and the occurrence of adverse reactions were observed. Results： The total effective rate was 82.22% in the control group, the total effective rate was 95.56% in the research group, thus the research group is with better efficacy（P〈0.05）; the control group were cured by time （8.21 ± 1.06） days, the healing time of the study group was （6.15 ± 1.05） day, compared with the control group, patients in the study group, the healing time was significantly shorter （P〈0.05）; the bacterial clearance rate was 77.78%, the study group of the bacterial clearance rate was 93.33%, with statistically significant （P〈0.05）; the incidence of adverse reaction in the control group was 8.89%, while the incidence of adverse reactions in the study group was 6.67% （P〉0.05）. Conclusion： Levofloxacin in the treatment of bacterial conjunctivitis is better, thus it is worth to be popularized.
出处
《药品评价》
CAS
2016年第13期49-52,共4页
Drug Evaluation
