摘要
目的探讨胱抑素C(CysC)在下肢血管病变中的临床意义。方法收集2015年2月至2015年8月在苏大附属第一人民医院介入科住院并确诊为有下肢血管病变的30例患者作为试验组,设置60例健康体检者作为对照组,采集他们的空腹静脉血,于促凝管中离心得到空腹血清,在全自动生化仪上采用胶乳增强免疫透射比浊法测定血清CysC的浓度。结果下肢血管病变患者血清CysC的浓度显著高于健康体检者(P<0.05),而且下肢血管病变病情严重患者CysC的浓度也显著高于下肢血管病变病情一般的患者(P<0.05)。下肢病变合并高血压的患者CysC的值显著高于单纯下肢血管病变的患者(P<0.05)。结论测定CysC在临床诊断下肢血管病变中具有临床意义,应用前景广阔。
Objective To investigate the clinical significance of cystatin C（CysC）in lower extremity angiopathy.Methods Thirty inpatients with lower extremity angiopathy in the intervention department of our hospital from February to August 2015 were collected as the experimental group and 60 individuals undergoing the healthy physical examination as the control group.The fasting venous blood was collected for obtaining the serum by centrifuging in pro-coagulation tube.Then the serum CysC concentration was detected by adopting the latex enhanced immune turbidimetric method in the fully automatic biochemical analyzer.Results The CysC concentration in the patients with lower extremity angopathy was significantly higher than that in the individuals undergoing healthy physical examination（P〈0.05）.Moreover the CysC concentration in the patients with severe lower extremity angiopathy was significantly higher than that in the patients with general condition of lower extremity angiopathy（P〈0.05）.The further study indicated that the CysC concentration had a certain significance in diagnosing whether lower extremity angiopathy complicating hypertension,the serum CysC value in the patients with complicating hypertension was significantly higher than that in the pure lower extremity angiopathy（P〈0.05）.Conclusion Measuring the CysC concentration has a clinical significance in clinical diagnosis of lower extremity angiopathy and has vast application prospect.
出处
《检验医学与临床》
CAS
2016年第18期2628-2630,共3页
Laboratory Medicine and Clinic
关键词
胱抑素C
下肢血管病变
高血压
cystatin C
lower extremity angiopathy
hypertension
