摘要
目的探讨影像学检测肿瘤直径和淋巴结转移在宫颈癌患者预后中的价值。方法 2008年-2012年157例在湖北省武汉市第八医院接受治疗的宫颈癌患者纳入本次研究。计算机体层摄影和/或磁共振成像检测肿瘤直径和淋巴结转移。比较肿瘤直径和淋巴结转移与临床病理因素的关系及对进展期宫颈癌预后的影响。结果单因素分析表明:8种参数具有预后显著意义,分别为阴道受累、病理学检测的淋巴结状态、肿瘤直径>6 cm、影像学检测的淋巴结状态、肾盂积水、膀胱/直肠受累、SCC-Ag含量>15 ng/ml和肿瘤分期。进一步多因素分析发现肿瘤直径和影像学检测的肿瘤直径是进展期宫颈癌患者的独立预后参数。结论肿瘤直径和影像学检测的肿瘤直径是进展期宫颈癌患者的独立预后参数。
Objective To investigate the prognostic role of tumor size and lymph node status determined by imaging in advanced cervical cancer patients. Methods The patients （ = 157） with stage IIA-IIB cervical cancer treated in our hospital between 2008 and 2012 were retrospectively enrolled. Tumor size and lymph node status were determined by CT and/or MRI. Correlations of tumor size and lymph node status with clinicopathological parameters and prognosis of advanced cervical cancer were analyzed. Results Univariate analysis showed 8 factors had remarkable prognostic significance. There were cancer stage, tumor size 〉6 cm, serum squamous cell carcinoma antigen level （SCC-Ag） 〉15 ng/ml, lower third vaginal involvement, hydronephrosis, bladder/rectum involvement, pelvic or para-aortic lymph node （LN） status detected by imaging, and pelvic LN metastasis identified by pathological examination. Furthermore, multivariate analysis revealed that tumor size and pelvic LN metastasis determined by imaging were the independent predictive variables. Conclusions Tumor size and pelvic LN metastasis measured by imaging are the independent predictive factors for the prognosis of advanced cervical cancer.
出处
《中国现代医学杂志》
CAS
北大核心
2016年第18期94-99,共6页
China Journal of Modern Medicine
关键词
宫颈癌
肿瘤直径
盆腔淋巴结
预后
uterine cervical cancer
tumor size
pelvic lymph node
prognosis
