摘要
目的观察通脉活血汤联合低分子肝素钙治疗脊柱术后下肢深静脉血栓形成的临床疗效。方法将60例患者按随机数字表法分为对照组与治疗组各30例,对照组给予低分子肝素钙治疗,治疗组给予通脉活血汤联合低分子肝素钙治疗,14 d后评价临床疗效。结果两组治疗后髌骨上方15 cm处腿围差、胫骨粗隆下方10 cm处腿围差、视觉模拟量表(VAS)评分、凝血功能及血液流变学指标(全血黏度低切、全血黏度高切、血浆黏度、红细胞压积)较治疗前均有改善(均P<0.05),且治疗组改善程度优于对照组(均P<0.05);治疗组总有效率93.33%高于对照组的80.00%(P<0.05)。两组在治疗过程中均未发生不良反应。结论通脉活血汤联合低分子肝素钙治疗脊柱术后下肢深静脉血栓形成,可改善凝血功能和血液流变学指标,减轻患肢肿胀、疼痛程度,提高临床疗效。
Objective： To observe clinical effect of Tongmai Huoxue Decoction combined with low molecular weight heparin calium on lower extremity deep venous thrombosis after spinal surgery. Methods： 60 cases were randomly divided into the control group and the treatment group, 30 cases in each. Low molecular weight heparin calium was given to the control group,while the treatment group received Tongmai Huoxue Decoction combined with low molecular weight heparin calium. Clinical effect was analyzed after 14 days. Results： After treatment, circumference differences of 15 cm above the patella and 10 cm below the fibia,VAS scores,coagulation function and blood rheology indexes （whole low viscosity,whole high viscosity,plasma viscosity,hematocrit） were im- proved, compared with before treatment （P〈 0.05）, and the improvement degree of the treatment group was better than that of the control group （P〈 0.05）. The total effective rate of the treatment group was 93.33% ,higher than that of the control group 80.00%（P〈0.05）. There were no adverse reactions in both groups during the course of treatment. Conclusion： Tongmai Huoxue Decoction combined with low molecular weight heparin calium on lower extremity deep venous thrombosis after spinal surgery can improve coagulation function and blood theology index- es, reduce limb swelling and pain, and improve clinical efficacy.
出处
《中国中医急症》
2016年第9期1780-1782,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
河北省唐山市科学技术局计划项目(13130247B)
关键词
下肢深静脉血栓形成
脊柱手术
通脉活血汤
低分子肝素钙
Lower extremity deep venous thrombosis
Spinal surgery
Tongmai Huoxue Decoction
Low molecu- lar weight heparin calium
