摘要
目的探讨中性粒细胞/淋巴细胞比值(NLR)与急性脑梗死(ACI)患者中医辨证分型的关系。方法选取250例ACI患者,设为脑梗死组,对其进行中医辨证分型,其中风痰瘀阻证68例、痰热腑实证62例、气虚血瘀证44例、风火上炎证39例及阴虚风动证37例,另选70例健康体检者作为正常对照组,检测所有入组者的血常规,并计算NLR,对各组NLR值进行统计学分析。结果与正常对照组相比,脑梗死组各中医证型亚组的NLR值均明显升高(P<0.01);各型亚组之间比较,风痰瘀阻证亚组的NLR值和痰热腑实证亚组的NLR值均明显高于风火上炎证、气虚血瘀证及阴虚风动证亚组(P<0.01),但风痰瘀阻证亚组与痰热腑实证亚组的NLR值比较差异无统计学意义(P>0.05)。结论 ACI中医证型与NLR值存在一定的相关性。
Objective To explore the relationship between neutrophil/lymphocyte ratio （NLR） and syndrome differentiation of traditional Chinese medicine in patients with acute cerebral infarction（ACI）. Methods 250 pa- tients with ACI were selected as the cerebral infarction group and then syndrome differentiated. The normal control group consisted of 70 healthy individuals. All of them were detected for blood routine and then NLR was calculat- ed. Results ACI patients were divided into wind-fire upward-invading syndrome（39 cases）, wind-phlegm-stasis syndrome（68 cases）, phlegm-heat-bowel excess syndrome（62 cases）, Qi-deficiency and blood-stasis syndrome（44 cases） and Yin-deficiency and wind syndrome（37 cases）. Compared with the normal control group,the levels of the NLR in the cerebral infarction groups were found to increase apparently（P〈0. 01）. Among different syndrome types,the levels of NLR in patients with the wind-phlegm-stasis syndrome and the phlegm-heat-bowel excess syn- drome were obviously higher than those in the wind-fire upward-invading syndrome group, the Qi-deficiency and blood-stasis syndrome group and the Yin-deficiency and wind syndrome group（P〈0.01）. However, there was no statistical difference between the wind-phlegm-stasis syndrome group and the phlegm-heat-bowel excess syndrome group（P〉0.05）. Conclusion A certain correlation exists in NLR and the syndrome differentiation of traditional Chinese medicine in patients with ACI.
出处
《中西医结合研究》
2016年第4期179-181,184,共4页
Research of Integrated Traditional Chinese and Western Medicine
关键词
急性脑梗死
中性粒细胞/淋巴细胞比值
炎症反应
中医辨证分型
acute cerebral infarction
neutrophil/lymphocyte ratio
inflammation
syndrome differentiation of traditional Chinese medicine
