摘要
目的探讨前列地尔治疗后循环缺血的临床效果。方法将96例后循环缺血患者按照随机、自愿的原则分为对照组和研究组，每组各48例。对照组患者给予常规治疗，研究组患者在常规治疗基础上加用前列地尔，疗程均为2周。比较两组患者治疗前后美国国立卫生院神经功能缺损评分（NIHSS）及治疗效果。结果研究组患者治疗后总有效率明显高于对照组患者，差异有统计学意义（91．67％VS75．00％，x2=5．636，P〈0．05）。两组患者治疗后两组NIHSS均明显降低，与治疗前相比均有统计学差异（均P〈0．05）；治疗后研究组患者下降更为明显，与对照组相比差异均有统计学意义（P〈0．05）。结论前列地尔能够明显改善后循环缺血患者的神经功能，疗效可靠，值得在临床中推广应用。
Objectlve To discuss the effect of alprostadil in patients with posterior circulation ischemia. Methods To- tally 96 cases with posterior circulation ischemia were divided randomly and voluntarily into the control group （ n = 48 ） and research group（ n = 48）. The patients of the control group were given conventional treatment and patients of the re- search group were given alprostadil based on the control group, courses were all two weeks. The national institutes of health neural function defect scale scores of before and after treatment of all patients and clinical effect were compared. Results The total effective rate of research group was significantly higher that of control group, the differences were sta- tistically significant （91.67 % vs 75.00%, X2 = 5. 636,P 〈 0. 05 ）. The NIHSS of all groups decreased after treatment （all P 〈 0. 05 ）, and the research group showed more obviously, the differences were statistically significant （ all P 〈 0. 05 ）. Conclusion Alprostadil can obviously improve the neurological function in patients with posterior circulation ischemia and the curative effect is reliable, it is worth popularization and application.
出处
《医药论坛杂志》
2016年第7期40-41,共2页
Journal of Medical Forum
关键词
后循环缺血
前列地尔
神经功能
疗效
Posterior circulation ischemia
Alprostadil
neurological function
Clinical effect
