摘要
目的探讨消渴丸联合六味地黄丸治疗气阴两虚2型糖尿病的临床疗效。方法选择2013年5月—2015年5月在志丹县人民医院进行诊治的气阴两虚2型糖尿病患者100例,随机分为观察组与对照组,每组各50例。对照组采用消渴丸治疗,观察组在对照组基础上加用六味地黄丸治疗,比较两组的治疗效果。结果观察组的总有效率为84.00%,明显高于对照组68.00%(P<0.05);两组患者治疗后的空腹血糖和餐后2 h血糖水平均明显低于治疗前(P<0.05),治疗后观察组的餐后2 h血糖水平明显低于对照组(P<0.05);观察组的气短懒言、惓息乏力、盗汗、自汗、口渴喜饮、五心烦热及便秘症状的治疗有效率明显高于对照组(P<0.05)。结论六味地黄丸联合消渴丸治疗气阴两虚2型糖尿病疗效显著,值得临床应用推广。
Objective To investigate the clinical effect of Xiaoke Pill combined with Liuwei Dihuang Pill in treating type 2 diabetes mellitus with Qi and Yin deficiency. Methods Totally 100 cases of patients with type 2 diabetes mellitus with Qi and Yin deficiency who were treated in Zhidan People＇s Hospital from May 2013 to May 2015 were selected and randomly divided into two groups, 50 cases in each group. The patients in observation group were treated with Xiaoke Pill combined with Liuwei Dihuang Pill, the patients in control group were treated with Xiaoke Pill, and the therapeutic effects of two groups were compared. Results The total effective rate in the observation group was 84.00%, significantly higher than that of 68.00% in the control group （P 〈 0.05）. Fasting blood glucose and postprandial 2 h blood glucose levels in the two groups were all significantly decreased after treatment （P 〈 0.05）, the postplandial 2 h blood glucose level in the observation group was significantly lower than that in the control group （P 〈 0.05）. The effective rate of clinical syndrome such as deficiency of Qi and disinclination to talk, tired and debihtation, night sweating, sweating, hydrodipsia and desire for drinks, large food intake with rapid hungering, dysphoria with feverish sensation in chest, palms and soles, constipated in observation group were significantly higher than control group （P 〈 0.05）. Conclusion The clinical effect of Xiaoke Pill combined with Liuwei Dihuang Pill in treating type 2 diabetes mellitus with Qi and Yin deficiency is significant effective and is worth promotion.
出处
《药物评价研究》
CAS
2016年第3期445-448,共4页
Drug Evaluation Research
关键词
消渴丸
六味地黄丸
气阴两虚
2型糖尿病
Liuwei Dihuang Pill
Xiaoke Pill
Qi and Yin deficiency
type 2 diabetes mellitus
