摘要
目的探讨联苯苄唑与硝酸咪康唑治疗婴幼儿念珠菌病疗效差异。方法以联苯苄唑(1%)和硝酸咪康唑(2%)治疗婴幼儿皮肤念珠菌病各30例,两种药物每日外用2次,疗程为2周,记录并比较两组患者用药1、2周时的疗效及不良反应。结果用药1周时联苯苄唑组治愈19例(63.3%),硝酸咪康唑组治愈10例(33.3%);两组有效率无明显统计学差异(P>0.05)。用药2周时,两组治愈率差异进一步扩大,联苯苄唑组治愈23例(76.7%),硝酸咪康唑组为11例(36.7%),两组有效率出现明显统计学差异(P<0.05),联苯苄唑组有效率(93.3%)明显高于硝酸咪康唑组(70.0%)。两组患者未见明显副作用。结论治疗婴幼儿皮肤念珠菌病联苯苄唑有效率高于硝酸咪康唑。
Objective To analyze differences of curative effects between bifonazole and miconazole nitrate to treat infant skin candidiasis. Methods Treating infant skin candidiasis with bifonazole (1% ) and miconazole nitrate(2 % ) for 30 patients respectively. Two drugs for external use only 2 times a day, course of treatment for 2 weeks, recording and compared curative effect and adverse reactions of the two kinds of drugs at one and two weeks. Results At one week, bifonazole cured 19 cases (63.3 % ), miconazole nitrate group of 10 cases were cured(33.3 %). There was no significant statistical difference between the two groups( P 〉 0.05). At two week, effective rate of bifonazole(93.3 % ) was obviously higher than miconazole nitrate(70.0 %, P 〈 0.05). There were no obvious side effects between the two groups. Conclusions Effective rate of bifonazole to infant skin candidiasis was higher than miconazole nitrate.
出处
《内蒙古医学杂志》
2016年第5期525-527,共3页
Inner Mongolia Medical Journal