摘要
目的:研究营养干预是否对行自体造血干细胞移植的IV期神经母细胞瘤(NB)的患儿有益。方法:2014年5月—2015年12月因NB拟行移植的患儿40例入组,随机分为营养干预组和常规治疗组,观察移植结束时患儿营养状况、并发症发生率。结果:移植结束时干预组体重减轻差值低于常规组(P<0.05);营养不良发生比例:干预组轻度7例、中度1例;常规组轻度9例、中度2例;干预组前白蛋白和白蛋白优于常规组(P<0.05),第3w饮食摄入量高于常规组,肠外营养支持时间、腹泻和肝功损伤发生率低于常规组(P均<0.05)。结论:对于IV期NB患儿,膳食营养指导及适量肠内营养补充有利于改善患儿的营养状况,提高患儿的治疗耐受性,有益于临床治疗。
【Objective】 To research whether it was beneficial to the patients with stage IV neuroblastoma undergoing autologous hematopoietic stem cell transplantation with the participation of the dietitian. 【Method】 Totally 40 patients with NB were randomly divided into nutritional intervention group and routine treatment group,and the nutritional status and complication rate were observed between May 2014 and December 2015. 【Result】 At the end of transplant intervention group weight loss difference was lower than normal group（ P 〈 0. 05）and the incidence of malnutrition in the intervention group was 7 cases,1 cases was mild,9 cases were mild,2 cases were moderat; prealbumin and albumin was better than that of routine group,3 weeks of dietary intake higher than conventional group. Parenteral nutrition support time、diarrhea and liver injury occurrence rate was lower than the routine group（ P 〈 0. 05）.【Conclusion】 For children with NB IV,the participation of the participation of the nutrition was conducive to maintaining the nutritional status of children,the participation of the dietitian had the advantage to the clinical treatment.
出处
《中国食物与营养》
2016年第8期85-88,共4页
Food and Nutrition in China
关键词
儿童
营养状况
Ⅳ期神经母细胞瘤
自体外周血干细胞移植
child
nutritional status
stage IV neuroblastoma
autologous peripheral blood stem cell transplantation
