摘要
目的分析吉林地区肠道病毒的病原学特征,为手足口病（HFMD）预防及治疗提供依据。方法 采集临床诊断为手足口病患者的咽拭子,用荧光定量RT-PCR对肠道病毒分型。结果 2014—2015年共检测1 662例,肠道病毒阳性率为80.81%,EV71、Cox A16和未定型肠道病毒阳性率分别16.55%、11.61%、52.65%。阳性病例男女性别比为1.38：1,0~4岁儿童阳性数占78.5%,发病较高月份为8~9月。结论2014—2015年吉林地区手足口病患者检出的肠道病毒主要为肠道病毒未定型,其感染率高于EV71和Cox A16,是引起吉林地区手足口病的主要病原体,提示对未定型肠道病毒需引起足够重视。0~4岁儿童发病率最高。发病高峰期为8~9月份,呈明显季节性。
Objective To analyze the etiological characteristics of enterovirus in Jilin region and provide basis for preventing and treating the hand-foot-and-mouth disease. Methods The throat swab of patients with hand-foot-and-mouth disease diagnosed in clinic was collected, and the enterovirus was classified by fluorescent quantitation RT-PCR. Results 1662 cases were detected from 2014 to 2015, the positive rate of enterovirus was 80.81%, the positive rates of EVT1, CoxA16 and uncommitted enterovirus were respectively 16.55%, 11.61% and 52.65%, the ratio of positive cases in male and female was 1.38：1, and the positive number of children aged from 0 to 4 was 78.5%, and the month with high incidence rate was between August and September. Conclusion The uncommitted enterovirus was the main enterovirus detected in patients with hand-foot-and-mouth disease in Jilin region from 2014 to 2015, the infection rate was higher than that of EV71 and CoxA16, which is the main pathogen of hand-foot-and-mouth disease in Jilin region, and it reminds us to pay enough attention to the uncommitted enterovirus, the incidence rate of children aged from 0 to 4 is the highest, and the incidence peak is from August to September, showing an obvious seasonality.
出处
《中国卫生产业》
2016年第21期78-80,共3页
China Health Industry
关键词
手足口病
肠道病毒
病原学
Hand-foot-and-mouth
Enterovirus
Etiology
