摘要
建立了农药制剂中48种非法添加杀虫剂的超高效液相色谱-四极杆-飞行时间质谱（UPLC-Q-TOF MS）快速 筛查方法.可湿性粉剂、乳油和悬浮剂3种剂型的农药制剂样品经甲醇溶解、提取后,采用UPLC-Q-TOF MS检测, 48种杀虫剂在0. 5-20 mg/L范围内线性关系良好,线性相关系数（五2）大于0. 99.48种农药的定量限为0. 05-0.4 mg/kg,检出限为0.01-0.2 mg/kg,低、中、高3个加标水平下的平均回收率为86.3 % -101 . 5 %,相对标准偏差 为1.7%-4.0%.该方法快速、准确,可用于农药制剂中多种杀虫剂的快速筛查.
An analytical method was established for the rapid screening of 48 illegally added insecticides in pesticide formulations by ultra performance liquid chromatography-quadrupole- time of flight mass spectrometry （UPLC-Q-TOF MS）. Three pesticide formulations of wettable powder,emulsifiable concentrate,suspension concentrate were extracted with methanol,then detected by UPLC-Q-TOF MS. The calibration curves were linear in the range of 0. 5-20 mg/L with the correlation coefficients more than 0. 99 for the 48 insecticides. The limits of quantification （LOQs） were 0. 05-0. 4 mg/kg. The limits of detection （LODs） were 0. 01-0. 2 mg/kg. The added recoveries for all the insecticides were 86. 3% -101. 5 % with the relative standard deviations ranging from 1.7% to 4.0%. This method has the characteristics of rapid and accurate screening,which can meet the requirement of the determination of the 48 insecticides in pesticide formulations.
出处
《色谱》
CAS
CSCD
北大核心
2016年第9期880-887,共8页
Chinese Journal of Chromatography
基金
上海市农委科技攻关项目(2015-4-6)~~
关键词
超高效液相色谱-四极杆-飞行时间质谱
快速筛查
杀虫剂
农药制剂
ultra performance liquid chromatography-quadruple-time of flight mass spectrometry （UPLC-Q-TOF MS）
rapid screening
pesticide formulations
insecticide
