摘要
慢性间质性膀胱炎/盆腔疼痛综合征(IC/PPS)是一种基于尿急、尿频、膀胱疼痛或盆腔部位疼痛的临床症候群,各种临床治疗方法效果不甚如人意。骶神经调节(SNM)作为一种新型的神经调控疗法,通过将倒刺电极放置于骶3或骶4神经根处进行微电调理,依靠脊髓中的上行-下达信号传输及大脑对刺激信号的整合,将失衡的膀胱、尿道、肠道、盆底肌肉等组织的功能恢复至正常。在对于保守治疗效果不佳的IC/PPS患者中,IC/PPS的Ⅰ-Ⅱ期手术转换率较高,SNM术后中、长期有效率高达68%~85%,SNM术后机械并发症发生率较高,比较常见的包括:电极移位、断裂和导线损坏,刺激器(IPG)植入部位感染及IPG损坏等。术前需要同患者详细沟通,术后需要接受定期随访,根据症状改善情况及时进行参数调整。
Interstitial cystitis/pelvic pain syndrome （IC/PPS） is a symptom complex consisting of symptoms including ur- gency, frequency, and pain in the bladder （related to filling/voiding） and/or pain in the pelvic region. Current pain manage- ment techniques do not provide satisfactory pain relief. As a new type of neural regulation therapy, sacral neuromodulation （SNM） puts the tined electrode through the third or fourth sacral nerve roots and exerts weak impulses on the sacral afferent nerve, depending on signal transmission through the spinal cord and brain integration of stimulation signal. SNM can normalize the function of bladder, urethral and pelvic organ, especially for these refractory cases. The long-term efficacy of SNM is as high as 68^--85 %. However, several complications still remain during permanent implantation stage, including dislocation, breaking and damage of electrode, and infection and damage of impulse generator （IPG） site. Careful communication should be considered before operation. Furthermore, regular follow-up and parameter adjustment are also needed after operation.
出处
《现代泌尿外科杂志》
CAS
2016年第8期573-576,共4页
Journal of Modern Urology
基金
北京市卫生系统高层次卫生技术人才培养项目(No.2015-3-030)
关键词
骶神经调节
间质性膀胱炎
盆腔疼痛综合征
sacral neuromodulation
interstitial cystitis
pelvic pain syndrome
