摘要
为了寻找具有较高除草活性的异香豆素类化合物,设计合成了16个新型异香豆素噁二唑类化合物4a^4p,其结构均经核磁共振氢谱、碳谱及高分辨质谱确证。初步除草活性测定结果表明,部分目标化合物在500 mg/L下对马唐Digitaria sanguinalis L.和反枝苋Amaranthus retroflexus L.具有一定的除草活性,其中化合物4j(4-[5-(4-氯-苯基)-[1,2,4]噁二唑-3-基]-3-己基-6,7-二甲氧基异香豆素)的活性最好,对马唐和反枝苋的致死率分别为64%和62%。
In order to get a series of isocoumarin compounds with high herbicidal activity, 16 substituted oxadiazole 4a-4p were synthesized. All the target compounds were characterized by^1 H NMR, ^13 C NMR and HRMS. Preliminary screening with Digitaria sanguinalis L. and Amaranthus retroflexus L. demonstrated that some of the target compounds exhibited herbicidal activity at the concentrations of 500 mg/L. 4j, 4-（5-（4-chlorophenyl）-1, 2, 4-oxadiazol-3-yl）-3-hexyl-6, 7-dimethoxy-1H-isochromen-1-one had the best effect to D. sanguinalis and A. retroflexus of which the mortality rates were 64% and 62%.
出处
《农药学学报》
CAS
CSCD
北大核心
2016年第4期530-534,共5页
Chinese Journal of Pesticide Science
基金
国家自然科学基金资助项目(31171877)
关键词
异香豆素
噁二唑
合成
除草活性
isocoumarin
oxadiazole
synthesis
herbicidal activity
