摘要
目的探讨连续性肾脏替代疗法（continunous renal replacement therapy,CRRT）在肾病综合症合并急性肾衰竭治疗中的临床效果。方法本次研究选取2011年1月~2015年1月间于新疆阿克苏地区第一人民医院治疗肾病综合征合并急性肾衰竭患者,共计98例。按随机数表法分为治疗组和对照组,各49例,对照组采用临床常规治疗内容,治疗组在上述基础上加用CRRT。对比两组患者的治疗效果。结果治疗前两组患者肾功能各项指标及电解质指标无显著差异（P〉0.05）;治疗后治疗组患者肾功能指标及电解质相关指标明显优于对照组（P〈0.05）。同时,治疗组患者不良反应事件发生次数均显著少于常规治疗患者且24小时尿量恢复600ml时间显著短于常规治疗组（P〈0.05）。结论 CRRT是一种有效治疗肾病综合症合并急性肾衰竭的临床方案,值得临床深入研究和广泛推广。
Objective To discuss the clinical effect of continunous renal replacement therapy （CRRT） on the treatment of nephrotic syndrome combined with acute renal failure. Methods 98 nephrotie syndrome patients who were combined with acute renal failure and were treated in the First People＇s Hospital of Aksu Area in XinJiang from January 2011 to January 2015 were selected. All cases were divided into experimental group and control group according to random number table,49 cases for each group. In control group patients were adopted clinically routine protocal, while experimental group were used CRRT additionally on the basis of routine protocal. Therapeutic effects were compared between two groups. Results Before treatment, there were no significant differences about renal function indicators and electrolyte indicators between two groups （P greater than 0.05）; After treatment, related indexes about renal function and electrolytes in the experimental group were significantly high compared with the control group （P 〈 0.05）. At the same time, the incidence of adverse effects in experimental group was significantly less than that of the control group and 24-hour urine recovery time was significantly shorter than that of the control group （P 〈 0.05）. Conclusion CRRT is a effective plan for treating nephrotic syndrome combined with acute renal failure, which deserves to be in-depth study clinically and is widely used.
出处
《新疆医学》
2016年第5期541-543,共3页
Xinjiang Medical Journal
关键词
CRRT
肾病综合征
急性肾衰竭
治疗效果
Continuous renal replacement therapy
Nephrotie syndrome
Acute renal failure
Therapeutic effect
