摘要
目的 分析我院药物不良反应（ADR）发生的特点。方法 对我院2015年发生的295份ADR报告,按患者的年龄、药物种类、给药途径等方面进行统计分析。结果 295份ADR报告中,患者年龄在0-18岁68例、19-39岁86例、40-59岁68例、≥60岁73例;给药途径为静脉滴注273例、口服9例、其他13例;按药物类别抗感染药142例、中成药和中药注射剂43例,抗感染药中,头孢菌素类72例,β-内酰胺抑制剂22例,其他抗感染药均不及20例;ADR累及器官/系统中,累及皮肤及其附件的180例,累及消化系统和循环系统均为26例,累及其他器官及系统均未超过20例。结论 我院19-39岁患者ADR发生率最高,出现ADR的主要给药途径是静脉滴注给药,出现ADR最多的药物是抗感染药,其中头孢类的抗感染药ADR发生率最高,ADR以皮肤及其附件损害为主。
Objective To investigate the characteristics of adverse drug reaction（ADR）in our hospital.Methods A statistical analysis was conducted on 295 ADR reports in our hospital in 2015,according to the age,type of drug,drug delivery and so on.Results Among 295 ADR cases,there were 68 cases for aged 0-18 years,86 cases for aged 19-39 years,68 cases for aged 40-59 years,73 cases for aged greater than or equal to 60.For administration route,there were273 cases of intravenous drip,9 cases of oral,and 13 cases of others.Anti-infective drugs were in 142 cases and Chinese patent medicine was in 43 cases.For anti-infective drugs,72 cases were cephalosporin,22 cases were β-lactams,other anti-infective drugs were less than 20 cases.Among ADR involved organs and systems,involving the skin and its appendages was 180 cases,involving the digestive system and circulatory system,were all 26 cases,involvement of other organs and systems did not exceed 20 cases.Conclusion For patients aged 19-39 years old were the highest incidence of ADR.The main administration route of ADR is intravenous administration and the most ADR drugs are anti-infective drugs,in which the cephalosporin was the highest.Lastly,ADR is given priority to damage the skin and accessories.
出处
《中国当代医药》
2016年第18期90-92,共3页
China Modern Medicine
