摘要
目的探讨神经导航引导下Ommaya囊置入术治疗颅内囊性占位的有效性及安全性。方法对广东省中医院神经外科自2007年1月至2014年12月收治的28例颅内囊性占位（包括囊性胶质瘤、囊性转移瘤、放射性脑病囊性坏死1患者，采用神经导航引导下Ommaya囊置入术治疗，并对患者的病历资料、病情转归、CT影像检查结果、手术治疗效果及术后并发症等进行回顾性分析。结果8例囊性胶质瘤患者中，临床症状和体征好转、13常生活能力提高者6例；影像学复查显示有效（病灶缩小〈50％）6例，有效率为75％。12例囊性转移瘤患者中，临床症状和体征好转、日常生活能力提高者9例；影像学复查显示有效9例，有效率为75％。8例放射性脑病囊性坏死患者中，临床症状和体征好转、日常生活能力提高者7例；影像学复查显示有效7例，有效率为87．5％。28例患者中无一例出现逆行颅内感染。结论神经导航引导下Ommaya囊置入术是颅内囊性占位的一种安全有效的治疗方法。
Objective To discuss the effectiveness and safety of Ommaya sar implantation through neuronavigation in treatment of intracranial cysts. Methods Twenty-eight patients with intracranial cysts （cystic glioma, cystic metastases, radioactive encephalopathy cystic necrosis）, admitted to our hospital from January 2007 to December 2014, were chosen in our study; these patients accepted Ommaya sar implantation through neuronavigation. The clinical data, disease courses, CT scan results, operation efficacies and postoperative complications of these patients were retrospectively analyzed. Results In the 8 patients with cystic gliomas, improvement of clinical symptoms and activity of daily living was noted in 6 patients; imaging re-check indicated focus shrink〈50% in 6 patients, enjoying an effective rate of 75%. In the 12 patients with cystic metastases, the improvement of clinical symptoms and activity of daily living was noted in 9 patients; imaging re-check indicated focus shrink〈50% in 9 patients, enjoying an effective rate of 75%. In the 8 patients with radioactive encephalopathy cystic necrosis, the improvement of clinical symptoms and activity of daily living was noted in 7 patients; imaging re-check indicated focus shrink〈50% in 7 patients, enjoying an effective rate of 87.5%. No antidromic intracranial infection was noted in these 28 patients. Conclusion Implantation of Ommaya sar through neuronavigation is an effective treatment in intracranial cysts, enjoying minimally invasiveness.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2016年第7期723-726,共4页
Chinese Journal of Neuromedicine
