摘要
椎基底动脉延长扩张综合征(VBD),病变主要累及颅内动脉的中膜层。延长扩张的动脉通常具有异常增粗的直径,但是动脉壁较薄;同时存在血管腔内血栓。主要临床表现包括急性脑缺血,进展性颅神经、脑干或第3脑室压迫以及急性血管破裂造成的灾难性后果。该病相对少见,但临床预后可能极差,为此,笔者对该病的病理学、病理生理过程、临床表现做一综述,以提高广大医务工作者对该病的认识。
Vertebralbasilar dolichoectasia (VBD) is a relatively rare condition affecting mainly the tunica media of the vertebrabasilar arteries with poor prognosis. As is characterized by elongation and distension of arteries, it commonly shows excessively enlarged vessel diameter with weakened vessel wails and is accompanied by, sometimes, thrombus. Patients with VBD may suffer from catastrophic consequences caused by acute cerebral ischemia, acute rupture of the vascular, or progressive compression of the cranial nerves, the brainstem or the third ventricle. In this review, the author gives an overview of the pathology, pathophysiology and clinical manifestation of VBD, in hope to provide clinicians with a better understanding of the disease.
出处
《中华神经创伤外科电子杂志》
2015年第6期46-49,共4页
Chinese Journal Of Neurotraumatic Surgery:Electronic Edition