摘要
目的 探讨铝碳酸镁与伊托必利联合治疗原发性胆汁返流性胃炎的疗效。方法 135例患者均为2014年10月－2015年5月期间我院收治的原发性胆汁返流性胃炎患者,按照治疗方法分为三组,A组、B组、C组,每组45例,三组患者分别采用伊托必利治疗、铝碳酸镁治疗、伊托必利与铝碳酸镁联合治疗。比较三组患者临床症状改善程度、总有效率、复发情况。结果 C组患者在腹痛、腹胀、恶心、呕吐等临床症状的改善程度均明显优于A组、B组,差异有统计学意义（P〈0.05）;A组呕吐的改善程度明显优于B组,差异有统计学意义（P〈0.05）。C组总有效率与A组、B作用比较明显更高,复发率与A组、B组比较更低,差异有统计学意义（P〈0.05）。结论 原发性胆汁返流性胃炎患者采用铝碳酸镁与伊托必利联合治疗疗效确切,可显著提高总有效率,促进临床症状的缓解,效果明显优于单独应用铝碳酸镁、伊托必利治疗,可在临床推广应用。
Objective The effect of primary bile reflux gastritis treated with Hydrotalcid and Itopride. Methods 135 cases were selected from October 2014 to May 2015 in our hospital patients with primary biliary reflux gastritis, who were divided into three groups, group A, group B, group C（n=45） according to the treatment methods. Three groups were treated with itopride, Hydrotalcid, itopride and Hydrotalcid. The degree of improvement in clinical symptoms, the total effective rate and recurrence of three groups were compared. Results The degree of improvement in abdominal pain, bloating, improve the degree of nausea, vomiting of group C were significantly better than group A, group B, the difference was statistically significant（P〈0.05）; The degree of improvement in vomiting of group A was better than group B, The difference was statistically significant（P〈0.05）. The total effective rate of group C was higher than group A, group B, Recurrence rate was lower, the difference was statistically significant（P〈0.05）. Conclusion The primary bile reflux gastritis patients with aluminum magnesium carbonate and Itopride combination therapy is effective, can significantly improve the overall efficiency, promote remission of clinical symptoms, better than alone Hydrotalcid, Ito will Li treatment, in clinical application.
出处
《中国继续医学教育》
2016年第14期166-168,共3页
China Continuing Medical Education
