摘要
目的探讨抗苗勒管激素(AMH)、抗卵巢抗体(AOAb)、抗子宫内膜抗体(AEAb)女性不孕的关系方法采用酶联免疫吸附实验ELISA和化学发光法对800例女性不孕患者和850例有生育史妇女进行AMH、AOAb和AEAb检测。结果女性不孕患者抗苗勒管激素AMH水平为6.01±1.17 ng/m L,明显高于对照组(P<0.05);抗子宫内膜抗体EMAb阳性率为10.25%,抗卵巢抗体AOAb阳性率为6.38%,阳性率都明显高于对照组(P<0.05)。结论 AMH、AOAb和AEAb与女性不孕密切相关,对临床诊断和治疗具有重要的指导意义。
Objective:To explore the relationship between the female patients with infertility and anti-mullerian hormone(AMH),anti-ovary antibody(AOAb),anti-edometrial antibody(AEAb). Methods:Enzyme linked immunosorbent assay(ELISA)and chemiluminoimmunoassay were used to determine the levels of AMH,AOAb and AEAb in 800 female patients with infertility and 850 cases of women with childbearing history. Results:The level of serum AMH is 6.01±1.17 ng/m L,The serum positive rate of AOAb and AEAb in male patients was 12.25%,6.38% in 800 female patients with infertility,respectively. The level of serum AMH and positive rate of AOAb and AEAb were significantly higher than control group(P〈0.05). Conclusion:AMH,AOAb和AEAb are closely associated with infertility and will provide important reference for diagnositic and treatment.
出处
《中国优生与遗传杂志》
2016年第7期106-107,共2页
Chinese Journal of Birth Health & Heredity