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女性不孕患者抗苗勒管激素、抗子宫内膜抗体和抗卵巢抗体检测分析 被引量:2

Analysis on anti-mullerian hormone,antiendometrial antibody and anti-ovary antibody of female patients with infertility
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摘要 目的探讨抗苗勒管激素(AMH)、抗卵巢抗体(AOAb)、抗子宫内膜抗体(AEAb)女性不孕的关系方法采用酶联免疫吸附实验ELISA和化学发光法对800例女性不孕患者和850例有生育史妇女进行AMH、AOAb和AEAb检测。结果女性不孕患者抗苗勒管激素AMH水平为6.01±1.17 ng/m L,明显高于对照组(P<0.05);抗子宫内膜抗体EMAb阳性率为10.25%,抗卵巢抗体AOAb阳性率为6.38%,阳性率都明显高于对照组(P<0.05)。结论 AMH、AOAb和AEAb与女性不孕密切相关,对临床诊断和治疗具有重要的指导意义。 Objective:To explore the relationship between the female patients with infertility and anti-mullerian hormone(AMH),anti-ovary antibody(AOAb),anti-edometrial antibody(AEAb). Methods:Enzyme linked immunosorbent assay(ELISA)and chemiluminoimmunoassay were used to determine the levels of AMH,AOAb and AEAb in 800 female patients with infertility and 850 cases of women with childbearing history. Results:The level of serum AMH is 6.01±1.17 ng/m L,The serum positive rate of AOAb and AEAb in male patients was 12.25%,6.38% in 800 female patients with infertility,respectively. The level of serum AMH and positive rate of AOAb and AEAb were significantly higher than control group(P〈0.05). Conclusion:AMH,AOAb和AEAb are closely associated with infertility and will provide important reference for diagnositic and treatment.
出处 《中国优生与遗传杂志》 2016年第7期106-107,共2页 Chinese Journal of Birth Health & Heredity
关键词 抗苗勒管激素 抗子宫内膜抗体 和抗卵巢抗体 不孕症 Anti-mullerian hormone Antiendometrial antibody Anti-ovary antibody Infertility
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  • 1林建华.卵巢自身免疫对生殖的影响[J].国外医学(计划生育分册),1995,14(4):193-195. 被引量:18
  • 2黄鹂,常笑雪.抗卵巢抗体在不明原因不孕、流产中的作用[J].陕西医学杂志,2005,34(8):950-951. 被引量:22
  • 3陈璟,蒋莉,陆亚.血清免疫抗体(AsAb、EmAb、AcAb、AoAb、ToxAb)检测在女性不孕不育症中的临床意义[J].放射免疫学杂志,2005,18(6):494-496. 被引量:10
  • 4Meduri G, Massin N, Guibourdenche J, el al. Serum anti- Mullerian hormone expression in women with premature ovarian failure[J]. Hum Reprod, 2007,22 ( 1 ) : 117-123. 被引量:1
  • 5Riggs RM, Duran EH, Baker MW, et al. Assessment of ovarian reserve with anti-Mullerian hormone:a comparison of the predictive value of anti-Mullerian hormone, folliclestimulating hormone,inhibin B, and age[J]. Am J Obstet Gynecol, 2008,199 ( 2 ) : 202-208. 被引量:1
  • 6Cameron IT, O' Shea FC. Occult ovarian failure: a syndrome of in,fertility, regular menses, and elevated folliclestimulating hormone concentrations[J]. J Clin Endocrinol Metab,1988,67(6) :1190-1194. 被引量:1
  • 7Knauff EA, Eijkemans MJ, I.ambalk CB, et al. Anti- Mullerian hormone,inhibin B,and antral follicle count in young women with ovarian failure[J]. J Clin Endocrinol Metab, 2009,94 ( 3 ) :786-792. 被引量:1
  • 8Hehenkamp WJ, Looman CW, Themmen AP, et al. Anti- Mullerian hormone levels in the spontaneous menstrual cycle do not show substantial fluctuation[J]. J Clin Endocrinol Metab,2006,91(10):4057-4063. 被引量:1
  • 9Rooij IA, Broekmans FJ, Velde ER, et al. Serum anti- Mullerian hormone levels:a novel measure of ovarian reserve[J]. Hum Reprod, 2002,17 (12): 3065-3071. 被引量:1
  • 10Seifer DB, Maclaughlin DT. Mullerian inhibiting substance levels and ovarian response. Fertil Steril, 2007, 88:539 - 546. 被引量:1

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