摘要
目的调查健康生育期女性血清抗苗勒管激素（AMH）水平,以探讨AMH的临床意义。方法选择100例健康生育期女性,根据月经周期和年龄分组,采用ELISA法检测血清AMH水平。结果生育期女性卵泡期AMH[（2.78±1.65）ng/ml]水平和黄体期[（3.06±1.78）ng/ml]比较,差异无统计学意义（P〉0.05）;生育期女性平均血清AMH水平[（2.85±1.66）ng/ml]与年龄呈负相关（r=-0.667,P〈0.001）。18~25岁女性AMH水平最高,可高达（4.25±1.23）ng/ml,随着年龄的增长而下降,41~47岁女性AMH水平降至（1.12±0.98）ng/ml。结论血清AMH水平在卵泡期和黄体期无明显差异,检测不限于卵泡期;年龄是影响AMH水平的重要因素,AMH的临床应用需结合年龄综合判断。
Objective To investigate the serum AMH level in domestic healthy reproductive age women,and to discuss the clinical application for AMH.Methods A total of 100 healthy reproductive age women participated in this study.All the subjects were grouped by menstrual cycle and age.Serum AMH concentration were measured by ELISA.Results AMH levels in follicular phase and luteal phase had no statistically differences.The average AMH level was（2.85 ± 1.66） ng / ml in reproductive age women.AMH level was negatively correlated to age（r=-0.667,P0.001）.It was（4.25±1.23）ng/ml in 18 to 25 year-old female,then declined with age increasing,and dropped significantly in 41 to 47 years old with the average level of（1.12±0.98） ng/ml.Conclusions Serum AMH level has no significantly difference in the follicular phase and luteal phase of the menstrual cycle.AMH detection is not limited to the follicular phase.Age is an important factor affecting the level of AMH,the clinical application of AMH should combine with age and need comprehensive judgment.
出处
《中国妇产科临床杂志》
2011年第4期281-283,共3页
Chinese Journal of Clinical Obstetrics and Gynecology
关键词
抗苗勒管激素
月经周期
年龄
卵巢储备功能
anti-Mullerian hormone
physiological menstrual cycle
age
ovarian reserve
