摘要
目的：观察注射用红花黄色素治疗稳定型心绞痛疗效和安全性。方法选取70例稳定型心绞痛患者，运用随机数字表法将患者分为观察组和对照组，各35例。观察组应用注射用红花素，对照组应用血塞通，比较两组疗效。结果观察组总有效率为94．3％，明显高于对照组的74．3％，差异有统计学意义（χ2＝5．285，P ＜0．01）。两组治疗后各临床指标均较治疗前明显改善，差异有统计学意义（t ＝13．021、25.407、3．376、3．930、7．119、10．163、18．044、3．765、3．124、6．096，均 P ＜0．05）；观察组心绞痛发作次数少于对照组，硝酸甘油用量低于对照组，差异均有统计学意义（t ＝4．686，6．568，均 P ＜0．05）。观察组总不良反应发生率为5．7％，与对照组的11．4％比较，差异无统计学意义（χ2＝0．729，P ＞0．05）。结论注射用红花黄色素治疗稳定型心绞痛疗效好，安全性高。
Objective To observe the efficacy and safety of safflower yellow injection in the treatment of sta-ble angina pectoris.Methods 70 patients with stable angina pectoris were selected and divided into observation group and control group by random number table method,35 cases in each group.The observation group used injection of safflower,and the control group used Xuesaitong.The effect was compared between the two groups.Results The total effective rate of the observation group was 94.3%,which was higher than 74.3% of the control group,the differ-ence was statistically significant（χ2 =5.285,P 〈0.01）.The clinical indexes of the two groups after treatment were significantly improved than before treatment,the differences were statistically significant （t =13.021,25.407,3.376, 3.930,7.119,10.163,18.044,3.765,3.124,6.096,all P 〈0.05）.The angina attack times of the observation group was less than that of the control group ,the dosage of nitroglycerin was lower than that of the control group ,the＆amp;nbsp;differences were statistically significant（t =4.686,6.568,all P 〈0.05）.The incidence rate of adverse reaction was 5.7% in the observation group,compared with the control group of 8.6%,the difference was not statistically signifi-cant（χ2 =0.729,P 〉0.05）.Conclusion The injection of safflower yellow pigment in the treatment of stable angina pectoris has high safety.
出处
《中国基层医药》
CAS
2016年第14期2205-2208,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
心绞痛
红花黄色素
治疗结果
Angina pectoris
Safflower yellow pigment
Treatment outcome
